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Query: KLC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KLC2 1 2.503 -0.210 0.230

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KLC2 Phosphorylation S581 0.652 1.621 _RAS(ph)SLNFLNK_
KLC2 Phosphorylation S610 0.504 0.953 _TLSSS(ph)SMDLSR_
KLC2 Phosphorylation S609 0.242 0.902 _TLSS(ph)SSMDLSR_
KLC2 Phosphorylation S582 0.561 0.719 _ASS(ph)LNFLNK_
KLC2 Phosphorylation S445 0.025 _VDS(ph)PTVNTTLR_
KLC2 Phosphorylation S589 -0.171 -0.720 _S(ph)VEEPTQPGGTGLSDSR_

Background Information for KLC2:


Pubmed-KLC2 »
Uniprot-KLC2 »
Biogrid-KLC2 »
ProteomicsDB-KLC2 »

Tumorportal-KLC2 »
COSMIC-KLC2 »
GenomeRNAi-KLC2 »
Genecards-KLC2


Protein-protein Interactions for KLC2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARX Cat. description Hein, Mann, Cell 2015
Category members IP bait CENPJ;DKFZp667E025 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP152 Cat. description Hein, Mann, Cell 2015
Category members IP bait GEMIN7 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF5B Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC4 Cat. description Hein, Mann, Cell 2015
Category members IP bait MIS12 Cat. description Hein, Mann, Cell 2015
Category members IP bait NCAPH Cat. description Hein, Mann, Cell 2015
Category members IP bait NIPBL Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP4C Cat. description Hein, Mann, Cell 2015
Category members IP bait RASSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC6 Cat. description Hein, Mann, Cell 2015
Category members IP bait SOD1 Cat. description Hein, Mann, Cell 2015
Category members IP bait AZIN1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf46 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CHRNA9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait COG6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DTNBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EID1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KLC1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KPTN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MOCS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MYCL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NAALADL2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUP43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SH3KBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait THEM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRAK2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KLC2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members Rabaptin_Rab5-bd_dom IPR015390 0.21
Category members Kinesin_light IPR002151 0.16


Protein complexes (CORUM database) featuring KLC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KLC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_1314 REACTOME_KINESINS 0 0.32
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members GO Category GO:0043005 neuron projection Database 0.08
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0035253 ciliary rootlet Database 0.03
Category members GO Category GO:0019894 kinesin binding Database 0.02
Category members GO Category GO:0008088 axon cargo transport Database 0


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