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bioLOGIC Data

Query: KIFAP3

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
KIFAP3	2	4.939	-0.390	0.750

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
KIFAP3	Phosphorylation	S60	2.143	2.221	_LKS(ph)LNANTDITSLAR_
KIFAP3	Ubiquitylation	K274		1.135	_YQGLVVK(gl)QEQLLR_
KIFAP3	Ubiquitylation	K380		0.772	_NK(gl)MVQVGLLPK_
KIFAP3	Ubiquitylation	K59	-1.310	0.084	_LK(gl)SLNANTDITSLAR_
KIFAP3	Ubiquitylation	K675		0.026	_IQSEK(gl)FR_
KIFAP3	Ubiquitylation	K479		-0.092	_ALKFK(gl)DPLLM(ox)K_
KIFAP3	Ubiquitylation	K477		-0.743	_ALK(gl)FKDPLLM(ox)K_

Background Information for KIFAP3:

Pubmed-KIFAP3 »

Uniprot-KIFAP3 »

Biogrid-KIFAP3 »

ProteomicsDB-KIFAP3 »

Tumorportal-KIFAP3 »

COSMIC-KIFAP3 »

GenomeRNAi-KIFAP3 »

Genecards-KIFAP3

Protein-protein Interactions for KIFAP3

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait KIF3A	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KIF3C	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KIFAP3	Cat. description	Hein, Mann, Cell 2015
Category members	IP bait KIFAP3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in KIFAP3

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	ARM-type_fold	IPR016024	9.26
Category members	Armadillo	IPR000225	1.58

Protein complexes (CORUM database) featuring KIFAP3

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring KIFAP3

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005829	cytosol	Database	INF
Category members	GO Category	GO:0005488	binding	Database	9.32
Category members	Pathway	Pathway_621	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	0	4.72
Category members	DDR Literature	pubmedid:19647519	Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation		3.6
Category members	Pathway	Pathway_458	REACTOME_IMMUNE_SYSTEM	0	3
Category members	GO Category	GO:0000794	condensed nuclear chromosome	Database	1.58
Category members	GO Category	GO:0007018	microtubule-based movement	Database	0.75
Category members	GO Category	GO:0005813	centrosome	Database	0.75
Category members	GO Category	GO:0005876	spindle microtubule	Database	0.68
Category members	GO Category	GO:0005783	endoplasmic reticulum	Database	0.62
Category members	Pathway	Pathway_1265	REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION	0	0.6
Category members	GO Category	GO:0006461	protein complex assembly	Database	0.57
Category members	GO Category	GO:0008104	protein localization	Database	0.5
Category members	Pathway	Pathway_53	REACTOME_HEMOSTASIS	0	0.4
Category members	GO Category	GO:0007596	blood coagulation	Database	0.4
Category members	Pathway	Pathway_1314	REACTOME_KINESINS	0	0.32
Category members	GO Category	GO:0007017	microtubule-based process	Database	0.3
Category members	GO Category	GO:0008285	negative regulation of cell proliferation	Database	0.28
Category members	GO Category	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	Database	0.13
Category members	Pathway	Pathway_385	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	0	0.07
Category members	GO Category	GO:0019894	kinesin binding	Database	0.02
Category members	GO Category	GO:0007165	signal transduction	Database	0
Category members	GO Category	GO:0016939	kinesin II complex	Database	0