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Query: KIF22

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
KIF22 0 -3.021 -0.380 0.440 -2.282 -0.477 0.069 -0.172 0.159

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
KIF22 Phosphorylation S543 0.090 -0.848 _AVVMPLQLIQEQAAS(ph)PNAEIHILK_
KIF22 Phosphorylation S412 -1.255 _GPEEEEIGS(ph)PEPMAAPASASQK_

Background Information for KIF22:


Pubmed-KIF22 »
Uniprot-KIF22 »
Biogrid-KIF22 »
ProteomicsDB-KIF22 »

Tumorportal-KIF22 »
COSMIC-KIF22 »
GenomeRNAi-KIF22 »
Genecards-KIF22


Protein-protein Interactions for KIF22
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait KIF22 Cat. description Hein, Mann, Cell 2015
Category members IP bait RBM45 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CNPY2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAPK14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in KIF22
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Hlx-hairpin-Hlx_DNA-bd_motif IPR003583 0.02
Category members Kinesin_motor_dom IPR001752 0
Category members RuvA_2-like IPR010994 0


Protein complexes (CORUM database) featuring KIF22
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring KIF22
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0000785 chromatin Database 2.59
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0008017 microtubule binding Database 0.79
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members GO Category GO:0005819 spindle Database 0.41
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members Pathway Pathway_1314 REACTOME_KINESINS 0 0.32
Category members GO Category GO:0005871 kinesin complex Database 0.27
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07


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