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Query: ISCU

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ISCU 0 0.775

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ISCU Ubiquitylation K54 0.775 _NVGSLDK(gl)TSK_
ISCU Ubiquitylation K57 0.775 _NVGSLDK(gl)TSK_

Background Information for ISCU:


Pubmed-ISCU »
Uniprot-ISCU »
Biogrid-ISCU »
ProteomicsDB-ISCU »

Tumorportal-ISCU »
COSMIC-ISCU »
GenomeRNAi-ISCU »
Genecards-ISCU


Protein-protein Interactions for ISCU
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait LONRF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM184A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ISCU
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring ISCU
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring ISCU
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0032947 protein complex scaffold Database 0.82
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0005506 iron ion binding Database 0.04
Category members GO Category GO:0016226 iron-sulfur cluster assembly Database 0
Category members GO Category GO:0051536 iron-sulfur cluster binding Database 0


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