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Query: IP6K2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IP6K2 0 -0.145 1.470 -0.720

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IP6K2 Ubiquitylation K309 -0.145 _ELLGPVLK(gl)K_
IP6K2 Ubiquitylation K222 -0.746 _YEVPCVLDLK(gl)MGTR_

Background Information for IP6K2:


Pubmed-IP6K2 »
Uniprot-IP6K2 »
Biogrid-IP6K2 »
ProteomicsDB-IP6K2 »

Tumorportal-IP6K2 »
COSMIC-IP6K2 »
GenomeRNAi-IP6K2 »
Genecards-IP6K2


Protein-protein Interactions for IP6K2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IP6K2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IP6K2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members IPK IPR005522 0.04


Protein complexes (CORUM database) featuring IP6K2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IP6K2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members Pathway Pathway_699 REACTOME_INTERFERON_SIGNALING 0 0.86
Category members GO Category GO:0019221 cytokine-mediated signaling pathway Database 0.44
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_505 REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM 0 0.33
Category members GO Category GO:0046854 phosphatidylinositol phosphorylation Database 0.31
Category members GO Category GO:0045111 intermediate filament cytoskeleton Database 0.26
Category members GO Category GO:0043065 positive regulation of apoptotic process Database 0.26
Category members GO Category GO:0030308 negative regulation of cell growth Database 0.18
Category members GO Category GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity Database 0.04
Category members Pathway Pathway_913 REACTOME_INTERFERON_ALPHA_BETA_SIGNALING 0 0
Category members GO Category GO:0000832 inositol hexakisphosphate 5-kinase activity Database 0
Category members GO Category GO:0006817 phosphate ion transport Database 0
Category members GO Category GO:0043647 inositol phosphate metabolic process Database 0
Category members GO Category GO:0052723 inositol hexakisphosphate 1-kinase activity Database 0
Category members GO Category GO:0052724 inositol hexakisphosphate 3-kinase activity Database 0
Category members GO Category GO:0060337 type I interferon signaling pathway Database 0


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