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Query: IKZF3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IKZF3 0 0.119 0.290 -0.100

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IKZF3 Phosphorylation S378 0.119 _GLS(ph)PNNSGHDSTDTDSNHEER_

Background Information for IKZF3:


Pubmed-IKZF3 »
Uniprot-IKZF3 »
Biogrid-IKZF3 »
ProteomicsDB-IKZF3 »

Tumorportal-IKZF3 »
COSMIC-IKZF3 »
GenomeRNAi-IKZF3 »
Genecards-IKZF3


Protein-protein Interactions for IKZF3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait IKZF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IKZF5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IKZF3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92


Protein complexes (CORUM database) featuring IKZF3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IKZF3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0007498 mesoderm development Database 0.58
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members Pathway Pathway_601 PID_IL2_1PATHWAY 0 0.1
Category members Pathway Pathway_591 BIOCARTA_IL2RB_PATHWAY 0 0
Category members GO Category GO:0030888 regulation of B cell proliferation Database 0
Category members GO Category GO:0042113 B cell activation Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0045577 regulation of B cell differentiation Database 0
Category members GO Category GO:0045619 regulation of lymphocyte differentiation Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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