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Query: IFT140

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
IFT140 0 0.549 0.160 0.210

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
IFT140 Ubiquitylation K1275 0.339 _NIIGFYTK(gl)GR_
IFT140 Ubiquitylation K1178 -0.698 _MTVAK(gl)DSSDLPEESRR_
IFT140 Ubiquitylation K188 -0.728 _ALDMFNWKK(gl)_
IFT140 Ubiquitylation K926 -1.020 _ALSYYEK(gl)SDTHR_
IFT140 Ubiquitylation K1040 -1.602 _AQAFK(gl)NAIR_
IFT140 Ubiquitylation K1077 -2.071 _YYEEK(gl)GVQMDR_

Background Information for IFT140:


Pubmed-IFT140 »
Uniprot-IFT140 »
Biogrid-IFT140 »
ProteomicsDB-IFT140 »

Tumorportal-IFT140 »
COSMIC-IFT140 »
GenomeRNAi-IFT140 »
Genecards-IFT140


Protein-protein Interactions for IFT140
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C11orf74 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C14orf179 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CRYL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DNAJC7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FEZ1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFT122 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TULP3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in IFT140
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members WD40_repeat_dom IPR017986 1.39
Category members WD40_repeat IPR001680 0.52


Protein complexes (CORUM database) featuring IFT140
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring IFT140
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0036064 ciliary basal body Database 0.05
Category members Disease phenotype Jeune_syndrome Jeune syndrome Database 0
Category members Disease phenotype Mainzer-Saldino_Syndrome Mainzer-Saldino Syndrome Database 0
Category members Disease phenotype Saldino-Mainzer_syndrome Saldino-Mainzer syndrome Database 0
Category members GO Category GO:0005929 cilium Database 0
Category members GO Category GO:0030991 intraciliary transport particle A Database 0
Category members GO Category GO:0032391 photoreceptor connecting cilium Database 0
Category members GO Category GO:0042384 cilium assembly Database 0


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