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Query: HSPH1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HSPH1 0 2.626 -0.310 0.000 -0.157 0.289
HSPH1 0 2.626 -0.310 0.000 -0.169 0.737 0.256

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HSPH1 Phosphorylation S811 0.531 0.626 _IES(ph)PKLER_
HSPH1 Ubiquitylation K353 0.098 0.212 _IPAVK(gl)ER_
HSPH1 Ubiquitylation K705 -0.399 0.190 _IGTPVK(gl)VR_
HSPH1 Ubiquitylation K196 -0.467 0.111 _QDLPSLDEK(gl)PR_
HSPH1 Ubiquitylation K358 -0.054 _IAK(gl)FFGK_
HSPH1 Ubiquitylation K473 0.301 _FVVQNVSAQK(gl)DGEK_
HSPH1 Ubiquitylation K587 -1.279 _KVDQPPEAK(gl)KPK_
HSPH1 Ubiquitylation K650 -0.130 _DK(gl)LCGPYEK_

Background Information for HSPH1:


Pubmed-HSPH1 »
Uniprot-HSPH1 »
Biogrid-HSPH1 »
ProteomicsDB-HSPH1 »

Tumorportal-HSPH1 »
COSMIC-HSPH1 »
GenomeRNAi-HSPH1 »
Genecards-HSPH1


Protein-protein Interactions for HSPH1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait HSPA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait HSPH1 Cat. description Hein, Mann, Cell 2015


Protein Domains in HSPH1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members HSP70_C IPR029048 0.66
Category members HSP70_peptide-bd IPR029047 0.55
Category members MreB_Mrl IPR004753 0.4
Category members Hsp_70_fam IPR013126 0.4


Protein complexes (CORUM database) featuring HSPH1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HSPH1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members DDR Literature pubmedid:TBD2_UV_increased Elia et al, 2015 UV increased acetylation events Elia et al. INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005576 extracellular region Database 10.9
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0006986 response to unfolded protein Database 0.62
Category members GO Category GO:0000902 cell morphogenesis Database 0
Category members GO Category GO:0006950 response to stress Database 0
Category members GO Category GO:0043014 alpha-tubulin binding Database 0
Category members GO Category GO:0045345 positive regulation of MHC class I biosynthetic process Database 0
Category members GO Category GO:0051085 chaperone mediated protein folding requiring cofactor Database 0
Category members GO Category GO:0051135 positive regulation of NK T cell activation Database 0


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