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Query: HMOX2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HMOX2 0 2.369 0.000 1.100 0.674 0.175

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HMOX2 Ubiquitylation K214 -0.356 0.716 _MNALDLNMK(gl)TK_
HMOX2 Ubiquitylation K259 -0.832 0.394 _ETLEDGFPVHDGK(gl)GDMR_
HMOX2 Ubiquitylation K24 -1.148 _NSGALEK(gl)ENQMR_
HMOX2 Ubiquitylation K38 -0.296 _MADLSELLK(gl)EGTK_
HMOX2 Ubiquitylation K216 -0.556 _MNALDLNMKTK(gl)_

Background Information for HMOX2:


Pubmed-HMOX2 »
Uniprot-HMOX2 »
Biogrid-HMOX2 »
ProteomicsDB-HMOX2 »

Tumorportal-HMOX2 »
COSMIC-HMOX2 »
GenomeRNAi-HMOX2 »
Genecards-HMOX2


Protein-protein Interactions for HMOX2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ABHD5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ACCN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C3AR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HMOX2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VIPR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HMOX2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Haem_Oase IPR002051 0
Category members Haem_Oase-like IPR016053 0
Category members Haem_Oase-like_multi-hlx IPR016084 0


Protein complexes (CORUM database) featuring HMOX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HMOX2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members Pathway Pathway_81 KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM 0 0.01
Category members Pathway Pathway_193 REACTOME_IRON_UPTAKE_AND_TRANSPORT 0 0
Category members Pathway Pathway_88 REACTOME_METABOLISM_OF_PORPHYRINS 0 0
Category members GO Category GO:0001666 response to hypoxia Database 0
Category members GO Category GO:0004392 heme oxygenase (decyclizing) activity Database 0
Category members GO Category GO:0006778 porphyrin-containing compound metabolic process Database 0
Category members GO Category GO:0006788 heme oxidation Database 0
Category members GO Category GO:0006879 cellular iron ion homeostasis Database 0
Category members GO Category GO:0006979 response to oxidative stress Database 0
Category members GO Category GO:0042167 heme catabolic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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