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bioLOGIC Data

Query: HIST1H2AG

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
HIST1H2AG	0	1.521			-0.438	0.112	0.401

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence
HIST1H2AG	Ubiquitylation	K96	0.928	0.630	_NDEELNK(gl)LLGK_
HIST1H2AG	Ubiquitylation	K120	0.042	0.241	_VTIAQGGVLPNIQAVLLPKK(gl)TESHHK_
HIST1H2AG	Ubiquitylation	K119	0.219	0.142	_VTIAQGGVLPNIQAVLLPK(gl)KTESHHK_
HIST1H2AG	Ubiquitylation	K126	0.224		_VTIAQGGVLPNIQAVLLPKKTESHHK(gl)_

Background Information for HIST1H2AG:

Pubmed-HIST1H2AG »

Uniprot-HIST1H2AG »

Biogrid-HIST1H2AG »

ProteomicsDB-HIST1H2AG »

Tumorportal-HIST1H2AG »

COSMIC-HIST1H2AG »

GenomeRNAi-HIST1H2AG »

Genecards-HIST1H2AG

Protein-protein Interactions for HIST1H2AG

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait APLF	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait COASY	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait E4F1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HIST1H2BA	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HIST1H3A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HMGN2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HSD3B2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait MAGEB10	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait POLB	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RAB11B	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait RBM34	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SART3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SDC2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SNRNP70	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TFG	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TRA2A	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait U2AF2	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait XPC	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait ZSCAN20	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in HIST1H2AG

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Histone_H2A	IPR002119	0.84
Category members	Histone_core_D	IPR007125	0.12
Category members	Histone-fold	IPR009072	0.01
Category members	CBFA_NFYB_domain	IPR003958	0

Protein complexes (CORUM database) featuring HIST1H2AG

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring HIST1H2AG

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005634	nucleus	Database	INF
Category members	GO Category	GO:0006334	nucleosome assembly	Database	3.77
Category members	GO Category	GO:0000786	nucleosome	Database	2.41
Category members	GO Category	GO:0019899	enzyme binding	Database	1.57
Category members	GO Category	GO:0003677	DNA binding	Database	1.53
Category members	Pathway	Pathway_889	KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS	0	0.9
Category members	GO Category	GO:0005622	intracellular	Database	0.32
Category members	GO Category	GO:0046982	protein heterodimerization activity	Database	0.28
Category members	GO Category	GO:0043565	sequence-specific DNA binding	Database	0.18