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Query: HIST1H2AD

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIST1H2AD 0 1.521 -0.438 0.112 0.401

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIST1H2AD Ubiquitylation K96 0.928 0.630 _NDEELNK(gl)LLGK_
HIST1H2AD Ubiquitylation K120 0.042 0.241 _VTIAQGGVLPNIQAVLLPKK(gl)TESHHK_
HIST1H2AD Ubiquitylation K119 0.219 0.142 _VTIAQGGVLPNIQAVLLPK(gl)KTESHHK_
HIST1H2AD Ubiquitylation K126 0.224 _VTIAQGGVLPNIQAVLLPKKTESHHK(gl)_

Background Information for HIST1H2AD:


Pubmed-HIST1H2AD »
Uniprot-HIST1H2AD »
Biogrid-HIST1H2AD »
ProteomicsDB-HIST1H2AD »

Tumorportal-HIST1H2AD »
COSMIC-HIST1H2AD »
GenomeRNAi-HIST1H2AD »
Genecards-HIST1H2AD


Protein-protein Interactions for HIST1H2AD
Show screen data for Category Name and Description Link to cat description Data Source


Protein Domains in HIST1H2AD
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Histone_H2A IPR002119 0.84
Category members Histone_core_D IPR007125 0.12
Category members Histone-fold IPR009072 0.01
Category members CBFA_NFYB_domain IPR003958 0


Protein complexes (CORUM database) featuring HIST1H2AD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HIST1H2AD
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members Pathway Pathway_320 REACTOME_CELL_CYCLE 0 11.08
Category members DDR Literature pubmedid:TBD1_UV_decreased Elia et al, 2015 UV decreased acetylation events Elia et al. 10.54
Category members Pathway Pathway_348 REACTOME_TRANSCRIPTION 0 9
Category members Pathway Pathway_351 REACTOME_RNA_POL_I_TRANSCRIPTION 0 8.31
Category members Pathway Pathway_350 REACTOME_RNA_POL_I_RNA_POL_III_AND_MITOCHONDRIAL_TRANSCRIPTION 0 7.97
Category members Pathway Pathway_884 REACTOME_MEIOTIC_SYNAPSIS 0 7.46
Category members Pathway Pathway_319 REACTOME_CHROMOSOME_MAINTENANCE 0 7.37
Category members Pathway Pathway_875 REACTOME_MEIOSIS 0 6.39
Category members Pathway Pathway_1281 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE 0 4.19
Category members Pathway Pathway_1312 REACTOME_PACKAGING_OF_TELOMERE_ENDS 0 4.09
Category members GO Category GO:0006334 nucleosome assembly Database 3.77
Category members Pathway Pathway_328 REACTOME_TELOMERE_MAINTENANCE 0 3.74
Category members Pathway Pathway_874 REACTOME_MEIOTIC_RECOMBINATION 0 3.7
Category members Pathway Pathway_1139 REACTOME_RNA_POL_I_PROMOTER_OPENING 0 3.56
Category members GO Category GO:0000786 nucleosome Database 2.41
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members Pathway Pathway_889 KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 0 0.9
Category members Pathway Pathway_920 REACTOME_AMYLOIDS 0 0.68
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18


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