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Query: HIC2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
HIC2 0 2.613 0.660 -0.600 -0.289 0.965 1.177 0.418 0.340

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
HIC2 Phosphorylation S348 0.387 -0.385 _KEPVAGS(ph)PFER_

Background Information for HIC2:


Pubmed-HIC2 »
Uniprot-HIC2 »
Biogrid-HIC2 »
ProteomicsDB-HIC2 »

Tumorportal-HIC2 »
COSMIC-HIC2 »
GenomeRNAi-HIC2 »
Genecards-HIC2


Protein-protein Interactions for HIC2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CALU Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CTBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait E4F1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MCF2L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRICKLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBCCD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWA5A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YY1AP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF169 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in HIC2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Znf_C2H2-like IPR015880 1.29
Category members Znf_C2H2 IPR007087 0.92
Category members BTB/POZ-like IPR000210 0.43
Category members BTB/POZ_fold IPR011333 0.36
Category members BTB_POZ IPR013069 0.32


Protein complexes (CORUM database) featuring HIC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring HIC2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0045892 negative regulation of transcription, DNA-dependent Database 1.15
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0005925 focal adhesion Database 0.68
Category members GO Category GO:0046872 metal ion binding Database 0


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