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Query: GTF3C1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GTF3C1 0 2.455 0.050 -0.600
GTF3C1 0 2.455 0.050 -0.600 -0.270 0.224 0.458 0.304 -0.025

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GTF3C1 Phosphorylation S1068 0.783 _NSSTDQGS(ph)DEEGSLQK_
GTF3C1 Ubiquitylation K1473 -0.060 0.770 _AFMECQK(gl)R_
GTF3C1 Phosphorylation S1611 0.187 _DGS(ph)LEDDEDEEDDLDEGVGGK_
GTF3C1 Ubiquitylation K958 -0.083 _QQLLYK(gl)R_
GTF3C1 Ubiquitylation K685 -0.345 -0.267 _TTVIQDGIK(gl)K_
GTF3C1 Ubiquitylation K1771 -0.608 _FSALEK(gl)AGGGR_
GTF3C1 Phosphorylation S1854 -1.343 -0.955 _PLEGSSSEDSPPEGQAPPS(ph)HSPR_
GTF3C1 Ubiquitylation K1325 -1.082 _YIVK(gl)NPQAYLNYK_
GTF3C1 Ubiquitylation K1535 -1.145 _AAGK(gl)LDQPDR_
GTF3C1 Ubiquitylation K130 -1.217 _TK(gl)SLQPR_
GTF3C1 Phosphorylation S1856 -1.073 -1.356 _PLEGSSSEDSPPEGQAPPSHS(ph)PR_
GTF3C1 Phosphorylation S739 -0.482 _TSQPPVPQGEAEEDS(ph)QGKEGPSGSGDSQLSASSR_
GTF3C1 Ubiquitylation K254 0.692 _SK(gl)YDILMEK_
GTF3C1 Ubiquitylation K382 -0.513 _RGTK(gl)GISQAEIR_
GTF3C1 Ubiquitylation K397 -1.377 _VAMNVGK(gl)LEAR_

Background Information for GTF3C1:


Pubmed-GTF3C1 »
Uniprot-GTF3C1 »
Biogrid-GTF3C1 »
ProteomicsDB-GTF3C1 »

Tumorportal-GTF3C1 »
COSMIC-GTF3C1 »
GenomeRNAi-GTF3C1 »
Genecards-GTF3C1


Protein-protein Interactions for GTF3C1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C3 Cat. description Hein, Mann, Cell 2015
Category members IP bait GTF3C4 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF19 Cat. description Hein, Mann, Cell 2015
Category members IP bait NUP98 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLR2F Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP6R1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SET Cat. description Hein, Mann, Cell 2015
Category members IP bait CD44 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR156 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GTF3C3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait INTU Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STX6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF764 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF785 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GTF3C1
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring GTF3C1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1106 TFIIIC containing-TOP1-SUB1 complex Database 0.72
Category members Corum 1114 5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex Database 0.25
Category members Corum 1101 TFIIIC containing complex TFIIIC2 Database 0.23
Category members Corum 1105 TFIIIC containing complex Database 0.23
Category members Corum 1113 5S-DNA-TFIIIA-TFIIIC2 subcomplex Database 0.08


Categories featuring GTF3C1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members GO Category GO:0006383 transcription from RNA polymerase III promoter Database 0.18
Category members GO Category GO:0009304 tRNA transcription Database 0.18
Category members GO Category GO:0000127 transcription factor TFIIIC complex Database 0.08
Category members GO Category GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter Database 0.08
Category members GO Category GO:0042797 tRNA transcription from RNA polymerase III promoter Database 0.08
Category members GO Category GO:0009303 rRNA transcription Database 0


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