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Query: GPR50

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GPR50 0 -0.562 0.770 -0.340 -0.384 -0.178

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for GPR50:


Pubmed-GPR50 »
Uniprot-GPR50 »
Biogrid-GPR50 »
ProteomicsDB-GPR50 »

Tumorportal-GPR50 »
COSMIC-GPR50 »
GenomeRNAi-GPR50 »
Genecards-GPR50


Protein-protein Interactions for GPR50
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CLEC2D Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPR114 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRPR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HLA-C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR2C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IPPK Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LPAR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SDC2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TACR1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM171 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TNFRSF1A Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GPR50
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members GPCR_Rhodpsn IPR000276 2.56
Category members GPCR_Rhodpsn_7TM IPR017452 2.32
Category members 7TM_GPCR_olfarory/Srsx IPR019424 0.46
Category members 7TM_GPCR_serpentine_rcpt_Srx IPR019430 0.24
Category members Melatonin_rcpt IPR000025 0.18
Category members NPY_rcpt IPR000611 0.03


Protein complexes (CORUM database) featuring GPR50
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GPR50
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members GO Category GO:0004930 G-protein coupled receptor activity Database 2.1
Category members Pathway Pathway_1184 KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 0 1.89
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0007186 G-protein coupled receptor signaling pathway Database 1.53
Category members GO Category GO:0007267 cell-cell signaling Database 0.94
Category members GO Category GO:0042802 identical protein binding Database 0.26
Category members GO Category GO:0008502 melatonin receptor activity Database 0.18


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