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Query: GOPC

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GOPC 0 0.152 -0.320 0.030

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GOPC Ubiquitylation K147 0.122 _TGQSADSGTIK(gl)AK_
GOPC Ubiquitylation K208 -1.015 _LAAK(gl)YLDK_

Background Information for GOPC:


Pubmed-GOPC »
Uniprot-GOPC »
Biogrid-GOPC »
ProteomicsDB-GOPC »

Tumorportal-GOPC »
COSMIC-GOPC »
GenomeRNAi-GOPC »
Genecards-GOPC


Protein-protein Interactions for GOPC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FYCO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait APBB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait BATF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C5orf24 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC102B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CCDC43 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EVI2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM174A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM9A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FKBP11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FXYD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GOPC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IFNG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait JUNB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MANBAL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MVP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NPM2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NUPL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCGF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RALBP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TBX22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TGOLN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF264 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF488 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GOPC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PDZ IPR001478 0.15


Protein complexes (CORUM database) featuring GOPC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GOPC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0043234 protein complex Database 2.73
Category members GO Category GO:0008022 protein C-terminus binding Database 1.43
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0006888 ER to Golgi vesicle-mediated transport Database 0.28
Category members GO Category GO:0005794 Golgi apparatus Database 0.27
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0007289 spermatid nucleus differentiation Database 0.18
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0030140 trans-Golgi network transport vesicle Database 0.03
Category members GO Category GO:0044325 ion channel binding Database 0.03
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0005083 small GTPase regulator activity Database 0
Category members GO Category GO:0005109 frizzled binding Database 0
Category members GO Category GO:0006893 Golgi to plasma membrane transport Database 0
Category members GO Category GO:0014069 postsynaptic density Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0042803 protein homodimerization activity Database 0
Category members GO Category GO:0045176 apical protein localization Database 0
Category members GO Category GO:0051260 protein homooligomerization Database 0


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