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Query: GMPPB

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GMPPB 0 0.654 -1.100 1.180 -0.526

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for GMPPB:


Pubmed-GMPPB »
Uniprot-GMPPB »
Biogrid-GMPPB »
ProteomicsDB-GMPPB »

Tumorportal-GMPPB »
COSMIC-GMPPB »
GenomeRNAi-GMPPB »
Genecards-GMPPB


Protein-protein Interactions for GMPPB
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait SESN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait GMPPB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GOLPH3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GMPPB
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Nucleotide-diphossugar_trans IPR029044 0.21
Category members NTP_transferase IPR005835 0.04


Protein complexes (CORUM database) featuring GMPPB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GMPPB
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Disease phenotype Congenital_muscular_dystrophy_with_cerebellar_involvement Congenital muscular dystrophy with cerebellar involvement Database 0.4
Category members Disease phenotype MUSCULAR_DYSTROPHY-DYSTROGLYCANOPATHY_(CONGENITAL_WITH_BRAIN_AND_EYE MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH BRAIN AND EYE Database 0.33
Category members GO Category GO:0006488 dolichol-linked oligosaccharide biosynthetic process Database 0.28
Category members Disease phenotype Congenital_muscular_dystrophy_with_intellectual_disability Congenital muscular dystrophy with intellectual disability Database 0.23
Category members Disease phenotype MUSCULAR_DYSTROPHY-DYSTROGLYCANOPATHY_(CONGENITAL_WITH_MENTAL_RETARDATION) MUSCULAR DYSTROPHY-DYSTROGLYCANOPATHY (CONGENITAL WITH MENTAL RETARDATION) Database 0.23
Category members Pathway Pathway_93 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN 0 0.18
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members Disease phenotype Muscle_eye_brain_disease Muscle eye brain disease Database 0.11
Category members GO Category GO:0009058 biosynthetic process Database 0.11
Category members Pathway Pathway_58 KEGG_FRUCTOSE_AND_MANNOSE_METABOLISM 0 0.1
Category members Pathway Pathway_61 KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM 0 0.04
Category members Pathway Pathway_92 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members GO Category GO:0009298 GDP-mannose biosynthetic process Database 0
Category members GO Category GO:0016779 nucleotidyltransferase activity Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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