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Query: GCDH

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GCDH 0 -0.645 1.160 -0.710 -0.423 -0.222

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for GCDH:


Pubmed-GCDH »
Uniprot-GCDH »
Biogrid-GCDH »
ProteomicsDB-GCDH »

Tumorportal-GCDH »
COSMIC-GCDH »
GenomeRNAi-GCDH »
Genecards-GCDH


Protein-protein Interactions for GCDH
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC12 Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait GCDH Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GCDH
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Acyl-CoA_Oxase/DH_cen-dom IPR006091 0
Category members AcylCo_DH/oxidase_C IPR009075 0
Category members AcylCoA_DH/oxidase_NM_dom IPR009100 0
Category members Acyl-CoA_DH_C_dom IPR013107 0
Category members AcylCoA_DH/ox_N IPR013786 0


Protein complexes (CORUM database) featuring GCDH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GCDH
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_22 KEGG_LYSINE_DEGRADATION 0 0.8
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_133 KEGG_FATTY_ACID_METABOLISM 0 0.31
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0050660 flavin adenine dinucleotide binding Database 0.12
Category members Pathway Pathway_37 KEGG_TRYPTOPHAN_METABOLISM 0 0.06
Category members GO Category GO:0034641 cellular nitrogen compound metabolic process Database 0.01
Category members Pathway Pathway_17 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES 0 0
Category members GO Category GO:0000062 fatty-acyl-CoA binding Database 0
Category members GO Category GO:0003995 acyl-CoA dehydrogenase activity Database 0
Category members GO Category GO:0006554 lysine catabolic process Database 0
Category members GO Category GO:0006568 tryptophan metabolic process Database 0
Category members GO Category GO:0006637 acyl-CoA metabolic process Database 0
Category members GO Category GO:0008152 metabolic process Database 0
Category members GO Category GO:0016491 oxidoreductase activity Database 0
Category members GO Category GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors Database 0
Category members GO Category GO:0019395 fatty acid oxidation Database 0
Category members GO Category GO:0046949 fatty-acyl-CoA biosynthetic process Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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