bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: GABRB3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GABRB3 0 0.445 0.420 -0.930

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GABRB3 Ubiquitylation K193 0.445 _SFVHGVTVK(gl)NR_

Background Information for GABRB3:


Pubmed-GABRB3 »
Uniprot-GABRB3 »
Biogrid-GABRB3 »
ProteomicsDB-GABRB3 »

Tumorportal-GABRB3 »
COSMIC-GABRB3 »
GenomeRNAi-GABRB3 »
Genecards-GABRB3


Protein-protein Interactions for GABRB3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACCN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GABRA6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GABRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MCOLN3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GABRB3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Neurotrans-gated_channel_TM IPR006029 0.09
Category members Neur_chan_lig-bd IPR006202 0.09
Category members Neur_channel IPR006201 0.08
Category members GABBAg_rcpt IPR005437 0.05
Category members GABAA/Glycine_rcpt IPR006028 0.04
Category members GABAAb_rcpt IPR002289 0


Protein complexes (CORUM database) featuring GABRB3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GABRB3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0016021 integral to membrane Database 7.67
Category members Pathway Pathway_1184 KEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION 0 1.89
Category members GO Category GO:0005887 integral to plasma membrane Database 1.69
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0043524 negative regulation of neuron apoptotic process Database 0.66
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0007268 synaptic transmission Database 0.23
Category members GO Category GO:0006811 ion transport Database 0.18
Category members GO Category GO:0055085 transmembrane transport Database 0.12
Category members Pathway Pathway_99 REACTOME_TRANSMEMBRANE_TRANSPORT_OF_SMALL_MOLECULES 0 0.08
Category members GO Category GO:0045211 postsynaptic membrane Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members Pathway Pathway_1242 REACTOME_GABA_A_RECEPTOR_ACTIVATION 0 0.05
Category members Pathway Pathway_1243 REACTOME_LIGAND_GATED_ION_CHANNEL_TRANSPORT 0 0.02
Category members GO Category GO:0005230 extracellular ligand-gated ion channel activity Database 0
Category members GO Category GO:0034707 chloride channel complex Database 0
Category members Pathway Pathway_139 REACTOME_NEURONAL_SYSTEM 0 0
Category members Pathway Pathway_140 REACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES 0 0
Category members Pathway Pathway_183 REACTOME_ION_CHANNEL_TRANSPORT 0 0
Category members Pathway Pathway_215 REACTOME_GABA_RECEPTOR_ACTIVATION 0 0
Category members Pathway Pathway_230 REACTOME_NEUROTRANSMITTER_RECEPTOR_BINDING_AND_DOWNSTREAM_TRANSMISSION_IN_THE_POSTSYNAPTIC_CELL 0 0
Category members Disease phenotype Childhood_absence_epilepsy Childhood absence epilepsy Database 0
Category members Disease phenotype epileptic_encephalopathies epileptic encephalopathies Database 0
Category members GO Category GO:0004890 GABA-A receptor activity Database 0
Category members GO Category GO:0005254 chloride channel activity Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0007605 sensory perception of sound Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0034220 ion transmembrane transport Database 0
Category members GO Category GO:0043523 regulation of neuron apoptotic process Database 0
Category members GO Category GO:0048666 neuron development Database 0
Category members GO Category GO:0060119 inner ear receptor cell development Database 0
Category members GO Category GO:0060384 innervation Database 0


.

© Copyright Svejstrup Laboratory 2015