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Query: GABPA

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
GABPA 0 0.710 -0.400 0.630
GABPA 0 0.710 -0.350 1.120

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
GABPA Ubiquitylation K359 -0.544 0.135 _LNQPELVAQK(gl)WGQR_

Background Information for GABPA:


Pubmed-GABPA »
Uniprot-GABPA »
Biogrid-GABPA »
ProteomicsDB-GABPA »

Tumorportal-GABPA »
COSMIC-GABPA »
GenomeRNAi-GABPA »
Genecards-GABPA


Protein-protein Interactions for GABPA
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GABPB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GABPB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TPD52L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait YEATS4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in GABPA
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members Ets_dom IPR000418 0.07
Category members Pointed_dom IPR003118 0
Category members SAM/pointed IPR013761 0


Protein complexes (CORUM database) featuring GABPA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring GABPA
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0003682 chromatin binding Database 6.07
Category members GO Category GO:0045653 negative regulation of megakaryocyte differentiation Database 4.97
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0000790 nuclear chromatin Database 0.46
Category members GO Category GO:0046982 protein heterodimerization activity Database 0.28
Category members GO Category GO:0001228 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Database 0.27
Category members GO Category GO:0001701 in utero embryonic development Database 0.2
Category members GO Category GO:0006357 regulation of transcription from RNA polymerase II promoter Database 0.19
Category members GO Category GO:0043565 sequence-specific DNA binding Database 0.18
Category members GO Category GO:0045944 positive regulation of transcription from RNA polymerase II promoter Database 0.13
Category members GO Category GO:0000122 negative regulation of transcription from RNA polymerase II promoter Database 0.02
Category members GO Category GO:0044212 transcription regulatory region DNA binding Database 0
Category members GO Category GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0


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