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Query: FXR1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FXR1 0 3.333 0.630 -0.330 -0.041 0.382 -0.062 0.362
FXR1 0 3.333 0.630 -0.330 0.287 0.508
FXR1 0 3.333 0.630 -0.330 0.529 0.083 0.357

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FXR1 Phosphorylation S601 0.394 0.422 _TDGS(ph)ISGDRQPVTVADYISR_
FXR1 Phosphorylation S409 -0.342 -0.106 _RGPNYTSGYGTNSELSNPS(ph)ETESER_
FXR1 Ubiquitylation K274 0.563 -0.128 _IYGESADAVKK(gl)_
FXR1 Ubiquitylation K299 0.113 -0.131 _NLVGKVIGK(gl)_
FXR1 Ubiquitylation K57 -1.779 _LPPPPDIKK(gl)_
FXR1 Ubiquitylation K119 -0.162 _LRPVNQNK(gl)TVK_
FXR1 Ubiquitylation K195 0.640 _TK(gl)LMLMSR_
FXR1 Ubiquitylation K207 0.358 _NEEATK(gl)HLECTK_
FXR1 Ubiquitylation K273 0.852 _IYGESADAVK(gl)K_
FXR1 Ubiquitylation K310 0.778 _VIQEIVDK(gl)SGVVR_
FXR1 Phosphorylation T598 0.270 _T(ph)DGSISGDRQPVTVADYISR_

Background Information for FXR1:


Pubmed-FXR1 »
Uniprot-FXR1 »
Biogrid-FXR1 »
ProteomicsDB-FXR1 »

Tumorportal-FXR1 »
COSMIC-FXR1 »
GenomeRNAi-FXR1 »
Genecards-FXR1


Protein-protein Interactions for FXR1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCLAF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCDC93 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCNA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCNB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK18 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP170P1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLU Cat. description Hein, Mann, Cell 2015
Category members IP bait KLC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait MTX1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH7B Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait PLK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCD Cat. description Hein, Mann, Cell 2015
Category members IP bait SAMM50 Cat. description Hein, Mann, Cell 2015
Category members IP bait SART3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLAIN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait SNCA Cat. description Hein, Mann, Cell 2015
Category members IP bait SPRED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait STMN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC1 Cat. description Hein, Mann, Cell 2015
Category members IP bait THOC2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TSNAX Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBA1C Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBA6 Cat. description Hein, Mann, Cell 2015
Category members IP bait FXR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LGALS3BP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAGEA4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PINX1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLEKHO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRP8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF512 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FXR1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members NA-bd_OB-fold IPR012340 4.37
Category members KH_dom IPR004087 0.23
Category members Agenet-like_dom IPR008395 0.17
Category members Frag_X_MRP_fam IPR022034 0.17
Category members KH_dom_type_1 IPR004088 0.13


Protein complexes (CORUM database) featuring FXR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5360 AGO2-FXR1-TNF(alpha)ARE-RNP complex Database 0.04


Categories featuring FXR1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members GO Category GO:0043034 costamere Database 1.42
Category members GO Category GO:0017148 negative regulation of translation Database 0.34
Category members GO Category GO:0003730 mRNA 3'-UTR binding Database 0.24
Category members GO Category GO:0005844 polysome Database 0.09
Category members GO Category GO:0030154 cell differentiation Database 0.06
Category members GO Category GO:0002151 G-quadruplex RNA binding Database 0
Category members GO Category GO:0007517 muscle organ development Database 0


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