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Query: FUBP1

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FUBP1 0 0.139 -0.530 0.120 0.095 -2.029
FUBP1 0 0.139 -0.530 0.120 -1.116 -0.826
FUBP1 0 0.139 -0.530 0.120 -1.002

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FUBP1 Ubiquitylation K400 0.642 1.251 _GGETIK(gl)SISQQSGAR_
FUBP1 Ubiquitylation K592 0.007 0.744 _AWEEYYKK(gl)_
FUBP1 Phosphorylation T174 0.487 0.294 _SCMLTGT(ph)PESVQSAK_
FUBP1 Ubiquitylation K133 -0.323 0.271 _IQQESGCK(gl)IQIAPDSGGLPER_
FUBP1 Ubiquitylation K312 -0.157 _IQFK(gl)PDDGTTPER_
FUBP1 Ubiquitylation K161 0.931 _SCMLTGTPESVQSAK(gl)R_

Background Information for FUBP1:


Pubmed-FUBP1 »
Uniprot-FUBP1 »
Biogrid-FUBP1 »
ProteomicsDB-FUBP1 »

Tumorportal-FUBP1 »
COSMIC-FUBP1 »
GenomeRNAi-FUBP1 »
Genecards-FUBP1


Protein-protein Interactions for FUBP1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BUB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP170P1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHMP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait RAB32 Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMAD3 Cat. description Hein, Mann, Cell 2015


Protein Domains in FUBP1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members KH_dom_type_2 IPR004044 0.34
Category members KH_dom IPR004087 0.23
Category members KH_dom_type_1 IPR004088 0.13
Category members DUF1897 IPR015096 0


Protein complexes (CORUM database) featuring FUBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FUBP1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0003697 single-stranded DNA binding Database 4.24
Category members GO Category GO:0006366 transcription from RNA polymerase II promoter Database 0.96
Category members GO Category GO:0003700 sequence-specific DNA binding transcription factor activity Database 0.63
Category members GO Category GO:0010628 positive regulation of gene expression Database 0


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