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Query: FMNL2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FMNL2 0 2.675 1.540 -0.760 0.647 0.873

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FMNL2 Phosphorylation S171 0.529 0.626 _S(ph)IEDLHR_
FMNL2 Phosphorylation S1018 0.250 0.320 _LLEQEALMEQQDPKSPS(ph)HK_
FMNL2 Phosphorylation S1016 -0.450 0.078 _LLEQEALMEQQDPKS(ph)PSHK_

Background Information for FMNL2:





Protein-protein Interactions for FMNL2

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CORO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait UNC119 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FMNL2

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members FH3_dom IPR010472 0.03
Category members GTPase-bd IPR010473 0.03
Category members FH2_Formin IPR015425 0
Category members Wilms_tumour IPR017987 0


Protein complexes (CORUM database) featuring FMNL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FMNL2

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0030036 actin cytoskeleton organization Database 1.08
Category members GO Category GO:0030866 cortical actin cytoskeleton organization Database 0.89
Category members GO Category GO:0017048 Rho GTPase binding Database 0.69
Category members GO Category GO:0016043 cellular component organization Database 0.03
Category members GO Category GO:0007010 cytoskeleton organization Database 0
Category members GO Category GO:0022604 regulation of cell morphogenesis Database 0


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