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Query: FKBP5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FKBP5 2 4.834 0.980 -0.750 -0.563

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FKBP5 Phosphorylation S445 2.419 2.011 _GTDS(ph)QAMEEEKPEGHV_
FKBP5 Phosphorylation S13 0.444 0.386 _NNEES(ph)PTATVAEQGEDITSK_
FKBP5 Ubiquitylation K352 1.350 -0.383 _ALGLDSANEK(gl)GLYR_
FKBP5 Ubiquitylation K385 -0.606 _VLEVNPQNK(gl)AAR_
FKBP5 Ubiquitylation K58 0.769 _VYVHYK(gl)GK_
FKBP5 Ubiquitylation K422 0.032 _FAEQDAK(gl)EEANK_
FKBP5 Phosphorylation T443 -0.653 _GT(ph)DSQAMEEEKPEGHV_

Background Information for FKBP5:


Pubmed-FKBP5 »
Uniprot-FKBP5 »
Biogrid-FKBP5 »
ProteomicsDB-FKBP5 »

Tumorportal-FKBP5 »
COSMIC-FKBP5 »
GenomeRNAi-FKBP5 »
Genecards-FKBP5


Protein-protein Interactions for FKBP5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait TINF2 Cat. description Hein, Mann, Cell 2015
Category members IP bait TMED2 Cat. description Hein, Mann, Cell 2015
Category members IP bait XRCC3 Cat. description Hein, Mann, Cell 2015
Category members IP bait ABHD15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AKT3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AMACR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ATG7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait AURKC Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK11A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK13 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK15 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDK9 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDKL1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CDKL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CLK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EIF2C3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAP3K6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MOS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NEK11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDIK1L Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PIPOX Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKACB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PSKH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SGK1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STK11 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STK35 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ULK3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR90 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FKBP5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members TPR_1 IPR001440 1.39
Category members TPR-contain_dom IPR013026 0.97
Category members TPR_repeat IPR019734 0.93
Category members PPIase_FKBP_dom IPR001179 0.31


Protein complexes (CORUM database) featuring FKBP5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5268 TNF-alpha/NF-kappa B signaling complex 7 Database 1.75
Category members Corum 5269 TNF-alpha/NF-kappa B signaling complex 8 Database 1.36
Category members Corum 5285 TNF-alpha/NF-kappa B signaling complex 9 Database 0.21


Categories featuring FKBP5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0006457 protein folding Database 4.93
Category members GO Category GO:0031072 heat shock protein binding Database 1.59
Category members GO Category GO:0003755 peptidyl-prolyl cis-trans isomerase activity Database 1.31
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_45 PID_REG_GR_PATHWAY 0 0.31
Category members GO Category GO:0000413 protein peptidyl-prolyl isomerization Database 0.25
Category members GO Category GO:0018208 peptidyl-proline modification Database 0.14
Category members GO Category GO:0005528 FK506 binding Database 0.06
Category members GO Category GO:0061077 chaperone-mediated protein folding Database 0


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