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Query: FEM1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FEM1A 0 0.741 0.270 -0.050

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FEM1A Ubiquitylation K15 -0.024 0.765 _DGK(gl)LQLLQK_
FEM1A Ubiquitylation K527 0.372 _LLK(gl)CAPR_

Background Information for FEM1A:


Pubmed-FEM1A »
Uniprot-FEM1A »
Biogrid-FEM1A »
ProteomicsDB-FEM1A »

Tumorportal-FEM1A »
COSMIC-FEM1A »
GenomeRNAi-FEM1A »
Genecards-FEM1A


Protein-protein Interactions for FEM1A
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANLN Cat. description Hein, Mann, Cell 2015
Category members IP bait KCTD5 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIAA1279 Cat. description Hein, Mann, Cell 2015
Category members IP bait MAGOH;MAGOHB Cat. description Hein, Mann, Cell 2015
Category members IP bait NLRP3 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDK17 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CUL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FEM1A
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ankyrin_rpt IPR002110 0
Category members Ankyrin_rpt-contain_dom IPR020683 0


Protein complexes (CORUM database) featuring FEM1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FEM1A
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0050728 negative regulation of inflammatory response Database 0
Category members GO Category GO:0051438 regulation of ubiquitin-protein ligase activity Database 0


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