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Query: FDPS

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FDPS 0 -0.239 0.900 -0.620 -0.782

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FDPS Ubiquitylation K210 0.306 _LLK(gl)LYCR_
FDPS Ubiquitylation K359 -0.930 -0.120 _ENYGQK(gl)EAEK(gl)VAR_
FDPS Ubiquitylation K112 -0.223 _LK(gl)EVLEYNAIGGK(gl)YNR_
FDPS Ubiquitylation K123 -1.471 -0.469 _LK(gl)EVLEYNAIGGK(gl)YNR_
FDPS Ubiquitylation K363 0.237 -1.039 _ENYGQK(gl)EAEK(gl)VAR_
FDPS Ubiquitylation K332 -0.588 _IGTDIQDNK(gl)CSWLVVQCLQR_
FDPS Ubiquitylation K353 -1.239 _ATPEQYQILK(gl)ENYGQK_

Background Information for FDPS:


Pubmed-FDPS »
Uniprot-FDPS »
Biogrid-FDPS »
ProteomicsDB-FDPS »

Tumorportal-FDPS »
COSMIC-FDPS »
GenomeRNAi-FDPS »
Genecards-FDPS


Protein-protein Interactions for FDPS
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C20orf7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FDPS Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FDPS
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Polyprenyl_synt IPR000092 0.04
Category members Terpenoid_synth IPR008949 0


Protein complexes (CORUM database) featuring FDPS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FDPS
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0044281 small molecule metabolic process Database 0.35
Category members Pathway Pathway_149 KEGG_TERPENOID_BACKBONE_BIOSYNTHESIS 0 0
Category members Pathway Pathway_164 REACTOME_CHOLESTEROL_BIOSYNTHESIS 0 0
Category members Pathway Pathway_4 REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS 0 0
Category members GO Category GO:0004161 dimethylallyltranstransferase activity Database 0
Category members GO Category GO:0006695 cholesterol biosynthetic process Database 0
Category members GO Category GO:0008299 isoprenoid biosynthetic process Database 0
Category members GO Category GO:0046872 metal ion binding Database 0


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