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Query: FBXO21

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FBXO21 1 3.957 -1.340 2.930

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FBXO21 Ubiquitylation K74 1.286 _VWK(gl)EQFR_
FBXO21 Ubiquitylation K356 0.926 _GK(gl)QLTVK_
FBXO21 Ubiquitylation K397 -0.258 0.758 _MVGNLLSLGK(gl)R_

Background Information for FBXO21:


Pubmed-FBXO21 »
Uniprot-FBXO21 »
Biogrid-FBXO21 »
ProteomicsDB-FBXO21 »

Tumorportal-FBXO21 »
COSMIC-FBXO21 »
GenomeRNAi-FBXO21 »
Genecards-FBXO21


Protein-protein Interactions for FBXO21
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FBXO21 Cat. description Hein, Mann, Cell 2015
Category members IP bait SKP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait ARSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EID1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IDS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KERA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRKCA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VWCE Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in FBXO21
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members F-box_dom IPR001810 0
Category members Hemimethylated_DNA-bd_dom IPR011722 0


Protein complexes (CORUM database) featuring FBXO21
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FBXO21
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0006511 ubiquitin-dependent protein catabolic process Database 3.57
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0000151 ubiquitin ligase complex Database 0.24
Category members GO Category GO:0004842 ubiquitin-protein ligase activity Database 0.24
Category members GO Category GO:0016567 protein ubiquitination Database 0.07


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