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Query: FANCI

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
FANCI 3 8.499 -0.230 -0.130 -0.878 0.258 0.641 1.631 0.954

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
FANCI Ubiquitylation K523 1.893 3.473 _K(gl)AMFANQLDARK_
FANCI Phosphorylation S407 -0.015 -0.064 _TIETS(ph)PSLSR_
FANCI Phosphorylation S409 -0.415 -0.284 _TIETSPS(ph)LSR_
FANCI Ubiquitylation K41 -0.316 _GK(gl)VAGALLR_
FANCI Ubiquitylation K148 0.699 -0.432 _ENLAYGK(gl)GVLSGEECKK_
FANCI Ubiquitylation K39 -0.484 _EGDLTNLLQNQAVK(gl)GK_
FANCI Ubiquitylation K52 -0.505 _AIFK(gl)GSPCSEEAGTLR_
FANCI Ubiquitylation K902 -0.694 _GK(gl)SISLLCLEGLQK_
FANCI Ubiquitylation K788 -0.698 _KLSDILNEK(gl)AGK_
FANCI Ubiquitylation K402 -0.883 -0.723 _VLDGK(gl)TIETSPSLSR_
FANCI Ubiquitylation K158 -0.795 _GVLSGEECKK(gl)_
FANCI Ubiquitylation K849 -0.807 _YAVNVALQK(gl)VQQLK_
FANCI Ubiquitylation K898 2.629 -0.994 _YTSIPTSVEESGKK(gl)_
FANCI Ubiquitylation K1230 -0.133 -1.162 _SLNYTGEKK(gl)_
FANCI Ubiquitylation K339 -1.516 _SFK(gl)DLQLLQGSK_
FANCI Ubiquitylation K397 -1.601 -1.698 _K(gl)VLDGKTIETSPSLSR_
FANCI Ubiquitylation K854 -1.893 _VQQLK(gl)ETGHVSGPDGQNPEK_
FANCI Ubiquitylation K715 -0.085 _MIK(gl)SELEDFELDK_
FANCI Ubiquitylation K1221 0.305 _SK(gl)SLNYTGEK_
FANCI Ubiquitylation K1269 0.901 _FLIHLSK(gl)K_

Background Information for FANCI:





Protein-protein Interactions for FANCI

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait FANCI Cat. description Hein, Mann, Cell 2015


Protein Domains in FANCI

Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring FANCI

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring FANCI

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005654 nucleoplasm Database INF
Category members GO Category GO:0006281 DNA repair Database INF
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_873 PID_FANCONI_PATHWAY 0 1.09
Category members GO Category GO:0007049 cell cycle Database 0.69
Category members Disease phenotype Fanconi_anemia Fanconi anemia Database 0.26
Category members Disease phenotype FANCONI_ANEMIA_COMPLEMENTATION_GROUP_A FANCONI ANEMIA COMPLEMENTATION GROUP A Database 0.2
Category members GO Category GO:0031398 positive regulation of protein ubiquitination Database 0


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