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Query: EXOC8

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EXOC8 1 2.609 0.140 -0.450 0.260 1.744

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EXOC8 Ubiquitylation K426 0.605 _LGQCTK(gl)ACELFLR_
EXOC8 Ubiquitylation K60 0.305 _IQALAEETAQNLK(gl)R_
EXOC8 Ubiquitylation K268 -0.971 _IFQAENAK(gl)IKR_

Background Information for EXOC8:


Pubmed-EXOC8 »
Uniprot-EXOC8 »
Biogrid-EXOC8 »
ProteomicsDB-EXOC8 »

Tumorportal-EXOC8 »
COSMIC-EXOC8 »
GenomeRNAi-EXOC8 »
Genecards-EXOC8


Protein-protein Interactions for EXOC8
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C19orf75 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPHA1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EXOC8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IL1R2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EXOC8
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Cullin_repeat-like_dom IPR016159 0.66
Category members PH_domain IPR001849 0.14


Protein complexes (CORUM database) featuring EXOC8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 89 Sec6/8 exocyst complex Database 0.07


Categories featuring EXOC8
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0030426 growth cone Database 1.61
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members Pathway Pathway_146 REACTOME_DIABETES_PATHWAYS 0 0.39
Category members GO Category GO:0006887 exocytosis Database 0.2
Category members GO Category GO:0034613 cellular protein localization Database 0.04
Category members Pathway Pathway_1256 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING 0 0
Category members GO Category GO:0000145 exocyst Database 0


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