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Query: ERC1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
ERC1 1 2.011 3.360 -0.900 0.057 -0.132

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
ERC1 Phosphorylation S21 1.090 0.996 _VEPSSQSPGRS(ph)PR_
ERC1 Phosphorylation S15 -0.220 _VEPSS(ph)QSPGRSPR_

Background Information for ERC1:


Pubmed-ERC1 »
Uniprot-ERC1 »
Biogrid-ERC1 »
ProteomicsDB-ERC1 »

Tumorportal-ERC1 »
COSMIC-ERC1 »
GenomeRNAi-ERC1 »
Genecards-ERC1


Protein-protein Interactions for ERC1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ACTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CD2AP Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait CHST15 Cat. description Hein, Mann, Cell 2015
Category members IP bait CKAP5 Cat. description Hein, Mann, Cell 2015
Category members IP bait DVL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF23 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF4A Cat. description Hein, Mann, Cell 2015
Category members IP bait MAPRE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait PPP1R21 Cat. description Hein, Mann, Cell 2015
Category members IP bait RACGAP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLC16A6 Cat. description Hein, Mann, Cell 2015
Category members IP bait GFOD1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait KBTBD7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SPERT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TSHB Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in ERC1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rab-bd_FIP-RBD IPR019018 0.04
Category members Prefoldin IPR009053 0
Category members CAZ_cplx_RIM-bd_prot IPR019323 0


Protein complexes (CORUM database) featuring ERC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 2118 CHUK-ERC1-IKBKB-IKBKG Database 0


Categories featuring ERC1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0015031 protein transport Database 3.48
Category members Disease phenotype THYROID_CARCINOMA_PAPILLARY THYROID CARCINOMA PAPILLARY Database 0.72
Category members GO Category GO:0007275 multicellular organismal development Database 0.31
Category members GO Category GO:0042147 retrograde transport, endosome to Golgi Database 0.26
Category members GO Category GO:0043522 leucine zipper domain binding Database 0.15
Category members GO Category GO:0008385 IkappaB kinase complex Database 0.13
Category members Disease phenotype Papillary_or_follicular_thyroid_carcinoma Papillary or follicular thyroid carcinoma Database 0.09
Category members Pathway Pathway_1051 PID_NFKAPPAB_CANONICAL_PATHWAY 0 0
Category members Pathway Pathway_631 PID_IL1_PATHWAY 0 0
Category members GO Category GO:0000139 Golgi membrane Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0007252 I-kappaB phosphorylation Database 0
Category members GO Category GO:0017137 Rab GTPase binding Database 0
Category members GO Category GO:0042734 presynaptic membrane Database 0
Category members GO Category GO:0051092 positive regulation of NF-kappaB transcription factor activity Database 0


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