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Query: EPB41L3

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EPB41L3 2 8.057 -0.180 -0.240
EPB41L3 2 8.057 -0.180 -0.240 0.686 -0.304 -0.569 0.493 0.521
EPB41L3 2 8.057 -0.180 -0.240 1.511 -0.048 0.066 -0.014

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EPB41L3 Ubiquitylation K65 1.020 1.593 _EVTDK(gl)EQEFAAR_
EPB41L3 Phosphorylation S793 0.573 1.236 _TETISFGSVS(ph)PGGVK_
EPB41L3 Phosphorylation T592 1.233 _RLS(ph)T(ph)SPVR_
EPB41L3 Phosphorylation S791 0.502 1.134 _TETISFGS(ph)VSPGGVK_
EPB41L3 Phosphorylation S88 0.840 1.043 _QLEYQQLEDDKLS(ph)QK_
EPB41L3 Phosphorylation T485 0.378 1.025 _GISQTNLITT(ph)VTPEKK_
EPB41L3 Phosphorylation S462 1.413 0.882 _DSM(ox)S(ph)AAEVGTGQYATTK_
EPB41L3 Phosphorylation S443 0.847 0.830 _S(ph)LDGASVNENHEIYMK_
EPB41L3 Phosphorylation S478 0.929 0.825 _GIS(ph)QTNLITTVT(ph)PEKK_
EPB41L3 Phosphorylation S593 0.571 0.742 _LSTS(ph)PVR_
EPB41L3 Ubiquitylation K570 1.272 0.676 _HQTNISELK(gl)R_
EPB41L3 Phosphorylation T487 0.317 0.583 _GIS(ph)QTNLITTVT(ph)PEK_
EPB41L3 Phosphorylation S448 0.617 0.533 _SLDGAS(ph)VNENHEIYMK_
EPB41L3 Phosphorylation S7 0.398 _TTESGS(ph)DSESKPDQEAEPQEAAGAQGR_
EPB41L3 Phosphorylation T510 -0.011 0.051 _KGEEVT(ph)PISAIR_
EPB41L3 Phosphorylation S420 -0.386 0.049 _RAS(ph)ALIDRPAPYFER_
EPB41L3 Phosphorylation S460 0.909 0.003 _DS(ph)MSAAEVGTGQYATTK_
EPB41L3 Phosphorylation S5 -0.015 _(ac)TTES(ph)GSDSESKPDQEAEPQEAAGAQGR_
EPB41L3 Phosphorylation T56 -1.710 _AGAPVPEPPKEEQQQALEQFAAAAAHS(ph)TPVRR_
EPB41L3 Phosphorylation S55 -1.826 _AGAPVPEPPKEEQQQALEQFAAAAAHS(ph)TPVRR_
EPB41L3 Ubiquitylation K75 1.272 _AAK(gl)QLEYQQLEDDKLSQK_
EPB41L3 Ubiquitylation K128 0.319 _VILLDGSEYTCDVEK(gl)R_
EPB41L3 Ubiquitylation K162 -0.060 _DAENQK(gl)NWLDPAK_
EPB41L3 Ubiquitylation K266 -0.008 _ELEDK(gl)VIELHK_
EPB41L3 Ubiquitylation K475 -0.076 _DSMSAAEVGTGQYATTK(gl)GISQTNLITTVTPEKK_
EPB41L3 Ubiquitylation K490 0.411 _GISQTNLITTVTPEK(gl)K_
EPB41L3 Ubiquitylation K491 0.411 _GISQTNLITTVTPEK(gl)K_
EPB41L3 Ubiquitylation K505 -0.213 _K(gl)GEEVTPISAIR_
EPB41L3 Ubiquitylation K588 0.598 _TFLETSTDTAVTNEWEK(gl)R_
EPB41L3 Phosphorylation T2 -0.189 _(ac)M(ox)T(ph)TESGSDSESKPDQEAEPQEAAGAQGR_
EPB41L3 Ubiquitylation K472 0.411 _GISQTNLITTVTPEK(gl)K_
EPB41L3 Ubiquitylation K473 0.411 _GISQTNLITTVTPEK(gl)K_
EPB41L3 Ubiquitylation K1061 0.496 _EAK(gl)EQHPDMSVTK_

Background Information for EPB41L3:


Pubmed-EPB41L3 »
Uniprot-EPB41L3 »
Biogrid-EPB41L3 »
ProteomicsDB-EPB41L3 »

Tumorportal-EPB41L3 »
COSMIC-EPB41L3 »
GenomeRNAi-EPB41L3 »
Genecards-EPB41L3


Protein-protein Interactions for EPB41L3
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ELMSAN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF1C Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF7 Cat. description Hein, Mann, Cell 2015
Category members IP bait C19orf21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CACNG5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CYP2S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDAH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRICKLE3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SNRPN Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EPB41L3
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members SAB_dom IPR007477 1.02
Category members Band_4.1_C IPR008379 1.02
Category members Band_41_protein IPR021187 1.02
Category members Ez/rad/moesin_like IPR000798 0.38
Category members FERM_N IPR018979 0.36
Category members FERM_PH-like_C IPR018980 0.35
Category members Band_41_fam IPR019750 0.33
Category members FERM-adjacent IPR014847 0.08
Category members FERM_domain IPR000299 0
Category members FERM_central IPR019748 0
Category members Band_41_domain IPR019749 0


Protein complexes (CORUM database) featuring EPB41L3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EPB41L3
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members GO Category GO:0006915 apoptotic process Database 2.12
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0005911 cell-cell junction Database 1.4
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0030866 cortical actin cytoskeleton organization Database 0.89
Category members GO Category GO:0007016 cytoskeletal anchoring at plasma membrane Database 0.74
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0043217 myelin maintenance Database 0.18
Category members GO Category GO:0002175 protein localization to paranode region of axon Database 0
Category members GO Category GO:0005200 structural constituent of cytoskeleton Database 0
Category members GO Category GO:0008150 biological_process Database 0
Category members GO Category GO:0008360 regulation of cell shape Database 0
Category members GO Category GO:0019898 extrinsic to membrane Database 0
Category members GO Category GO:0030673 axolemma Database 0
Category members GO Category GO:0030913 paranodal junction assembly Database 0
Category members GO Category GO:0033270 paranode region of axon Database 0
Category members GO Category GO:0044224 juxtaparanode region of axon Database 0
Category members GO Category GO:0048812 neuron projection morphogenesis Database 0
Category members GO Category GO:0071205 protein localization to juxtaparanode region of axon Database 0


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