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Query: EPB41L2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EPB41L2 2 10.318 0.660 0.421 0.482
EPB41L2 2 10.318 1.324

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EPB41L2 Ubiquitylation K86 0.958 3.487 _QK(gl)SYTLVVAK_
EPB41L2 Ubiquitylation K206 1.268 1.978 _EVQTNELKAEK(gl)ASQK_
EPB41L2 Ubiquitylation K221 1.602 1.745 _TVQCK(gl)VTLLDGTEYSCDLEK_
EPB41L2 Ubiquitylation K203 1.218 1.588 _EVQTNELK(gl)AEK_
EPB41L2 Ubiquitylation K652 0.911 1.473 _HQASISELK(gl)R_
EPB41L2 Phosphorylation S87 0.973 1.442 _QKS(ph)YTLVVAK_
EPB41L2 Ubiquitylation K126 1.508 1.259 _QAK(gl)GDAEEMAQK_
EPB41L2 Ubiquitylation K135 1.116 _GDAEEMAQK(gl)K_
EPB41L2 Ubiquitylation K136 1.348 1.116 _GDAEEMAQKK(gl)_
EPB41L2 Ubiquitylation K171 0.192 1.031 _VEMQPTELVSK(gl)ER_
EPB41L2 Phosphorylation T600 0.196 1.031 _EVRSPT(ph)KAPHLQLIEGK_
EPB41L2 Ubiquitylation K12 1.250 1.003 _(ac)TTEVGSVSEVK(gl)K_
EPB41L2 Phosphorylation T89 0.996 _KQKSYT(ph)LVVAK_
EPB41L2 Ubiquitylation K195 1.159 0.966 _ETK(gl)EVQTNELK_
EPB41L2 Phosphorylation S614 1.409 0.697 _NS(ph)LRVEGDNIYVR_
EPB41L2 Phosphorylation S715 0.054 0.619 _EIS(ph)PGSGPGEIR_
EPB41L2 Phosphorylation S598 0.446 0.515 _EVRS(ph)PTKAPHLQLIEGK_
EPB41L2 Phosphorylation S683 0.419 0.437 _ITPLSLQTQGSS(ph)HETLNIVEEK_
EPB41L2 Phosphorylation S550 -0.082 0.432 _S(ph)LDGAPIGVM(ox)DQSLM(ox)K_
EPB41L2 Ubiquitylation K24 0.972 0.412 _DSSQLGTDATK(gl)EKPK_
EPB41L2 Phosphorylation T686 0.393 _ITPLSLQTQGSSHET(ph)LNIVEEK_
EPB41L2 Phosphorylation S647 0.292 _HQAS(ph)ISELKR_
EPB41L2 Phosphorylation S386 0.306 0.192 _GLS(ph)PAQADSQFLENAK_
EPB41L2 Ubiquitylation K892 0.014 0.122 _TEISTK(gl)EVPIVQTETK_
EPB41L2 Phosphorylation S55 -0.274 -0.402 _GSQPPPAAES(ph)QSSLRR_
EPB41L2 Phosphorylation S718 -0.336 -0.512 _EISPGS(ph)GPGEIR_
EPB41L2 Phosphorylation S38 -0.631 -0.778 _EVAENQQNQS(ph)SDPEEEKGSQPPPAAESQSSLR_
EPB41L2 Phosphorylation S39 -0.631 -0.778 _EVAENQQNQS(ph)SDPEEEKGSQPPPAAESQSSLR_
EPB41L2 Phosphorylation S499 -0.659 -0.888 _LVS(ph)PEQPPK_
EPB41L2 Phosphorylation S58 -0.353 -1.316 _GSQPPPAAESQSS(ph)LRR_
EPB41L2 Ubiquitylation K623 1.098 _SSHETLNIVEEK(gl)K_
EPB41L2 Ubiquitylation K13 1.753 _TTEVGSVSEVKK(gl)_
EPB41L2 Phosphorylation S57 -0.615 _EVAENQQNQSSDPEEEKGSQPPPAAESQS(ph)SLRR_
EPB41L2 Ubiquitylation K84 1.674 _K(gl)QK(gl)SYTLVVAK_
EPB41L2 Ubiquitylation K160 0.320 _EEKPSVSK(gl)VEMQPTELVSK_
EPB41L2 Ubiquitylation K178 0.801 _VK(gl)ETQEDKLEGGAAK_
EPB41L2 Ubiquitylation K184 1.056 _VKETQEDK(gl)LEGGAAK_
EPB41L2 Ubiquitylation K374 0.322 _ELEEK(gl)VAELHK_
EPB41L2 Ubiquitylation K399 0.325 _GLSPAQADSQFLENAK(gl)R_
EPB41L2 Ubiquitylation K601 0.190 _SPTK(gl)APHLQLIEGK_
EPB41L2 Ubiquitylation K611 0.767 _APHLQLIEGK(gl)K_
EPB41L2 Ubiquitylation K612 0.767 _APHLQLIEGK(gl)K_
EPB41L2 Phosphorylation S676 0.385 _ITPLS(ph)LQTQGSSHETLNIVEEK_
EPB41L2 Phosphorylation T679 0.261 _ITPLSLQT(ph)QGSSHETLNIVEEK_
EPB41L2 Ubiquitylation K946 0.682 _TVK(gl)GGISETR_

Background Information for EPB41L2:


Pubmed-EPB41L2 »
Uniprot-EPB41L2 »
Biogrid-EPB41L2 »
ProteomicsDB-EPB41L2 »

Tumorportal-EPB41L2 »
COSMIC-EPB41L2 »
GenomeRNAi-EPB41L2 »
Genecards-EPB41L2


Protein-protein Interactions for EPB41L2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAX6 Cat. description Hein, Mann, Cell 2015
Category members IP bait CYP2S1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DDAH2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EPB41L2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GJB7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MLF1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait WDR59 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EPB41L2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Ubiquitin-rel_dom IPR029071 1.79
Category members SAB_dom IPR007477 1.02
Category members Band_4.1_C IPR008379 1.02
Category members Band_41_protein IPR021187 1.02
Category members Ez/rad/moesin_like IPR000798 0.38
Category members FERM_N IPR018979 0.36
Category members FERM_PH-like_C IPR018980 0.35
Category members Band_41_fam IPR019750 0.33
Category members FERM-adjacent IPR014847 0.08
Category members FERM_domain IPR000299 0
Category members FERM_central IPR019748 0
Category members Band_41_domain IPR019749 0


Protein complexes (CORUM database) featuring EPB41L2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EPB41L2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0003779 actin binding Database 5.41
Category members Pathway Pathway_413 KEGG_TIGHT_JUNCTION 0 2.08
Category members GO Category GO:0008180 COP9 signalosome Database 1.47
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0030507 spectrin binding Database 1.12
Category members GO Category GO:0005198 structural molecule activity Database 0.94
Category members GO Category GO:0030866 cortical actin cytoskeleton organization Database 0.89
Category members GO Category GO:0005856 cytoskeleton Database 0.63
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0008091 spectrin Database 0.43
Category members GO Category GO:0042731 PH domain binding Database 0.11
Category members GO Category GO:0019898 extrinsic to membrane Database 0
Category members GO Category GO:0030054 cell junction Database 0


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