bioLOGIC Data » bioLOGIC CategoryView » bioLOGIC VennView » Experimental Details »

bioLOGIC Data

bioLOGIC Data


Exact search


Query: EML4

This is a cancer-associated gene according to the Sanger cancer gene census.

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
W
[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EML4 0 1.400 -0.380 -0.100
EML4 0 1.400 -0.380 -0.100 -0.351 0.137 -0.060

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EML4 Phosphorylation S7 -0.650 1.378 _(ac)MDGFAGS(ph)LDDSISAASTSDVQDR_
EML4 Phosphorylation S11 0.559 _(ac)MDGFAGSLDDS(ph)ISAASTSDVQDR_
EML4 Phosphorylation S144 -1.107 -0.553 _AS(ph)PSPQPSSQPLQIHR_
EML4 Phosphorylation S146 -1.217 -0.631 _ASPS(ph)PQPSSQPLQIHR_
EML4 Phosphorylation T908 -1.723 -1.649 _APVSSTESVIQSNT(ph)PTPPPSQPLNETAEEESR_
EML4 Ubiquitylation K64 -0.220 _LAISEDHVASVKK(gl)_
EML4 Phosphorylation S16 0.616 _(ac)MDGFAGSLDDSISAAS(ph)TSDVQDR_

Background Information for EML4:


Pubmed-EML4 »
Uniprot-EML4 »
Biogrid-EML4 »
ProteomicsDB-EML4 »

Tumorportal-EML4 »
COSMIC-EML4 »
GenomeRNAi-EML4 »
Genecards-EML4


Protein-protein Interactions for EML4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait NEK9 Cat. description Hein, Mann, Cell 2015
Category members IP bait TFEB Cat. description Hein, Mann, Cell 2015
Category members IP bait CTAGE5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait EML1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FBXO28 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PHKG2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PRPS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TKT Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB2A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB2B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TUBB3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EML4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members WD40_repeat_dom IPR017986 1.39
Category members Quinonprotein_ADH-like_supfam IPR011047 0.56
Category members WD40_repeat IPR001680 0.52
Category members HELP IPR005108 0


Protein complexes (CORUM database) featuring EML4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EML4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members Human mutations Sanger_cancer_genes Sanger cancer genes Database 4.88
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0007017 microtubule-based process Database 0.3
Category members GO Category GO:0003674 molecular_function Database 0.08
Category members GO Category GO:0007026 negative regulation of microtubule depolymerization Database 0


.

© Copyright Svejstrup Laboratory 2015