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Query: EIF6

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EIF6 0 0.264 -0.610 0.240

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EIF6 Phosphorylation S235 0.532 _LNEAQPSTIATS(ph)M(ox)RDSLIDSLT_
EIF6 Phosphorylation S239 -0.389 0.417 _LNEAQPSTIATSM(ox)RDS(ph)LIDSLT_
EIF6 Ubiquitylation K54 -0.119 _CGGSPGAYGGGEACAGVK(gl)SSGSGR_

Background Information for EIF6:


Pubmed-EIF6 »
Uniprot-EIF6 »
Biogrid-EIF6 »
ProteomicsDB-EIF6 »

Tumorportal-EIF6 »
COSMIC-EIF6 »
GenomeRNAi-EIF6 »
Genecards-EIF6


Protein-protein Interactions for EIF6
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CNOT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPD Cat. description Hein, Mann, Cell 2015
Category members IP bait PHF8 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait BCCIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EIF6
Domain name Domain Description TC-NER relevance -log10(p-value)


Protein complexes (CORUM database) featuring EIF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5380 TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle) Database 5.3
Category members Corum 5378 TRBP containing complex (DICER, TRBP, AGO2, RPL7A, EIF6, MOV10) Database 0


Categories featuring EIF6
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005638 lamin filament Database 0.89
Category members Pathway Pathway_1274 BIOCARTA_EIF_PATHWAY 0 0.78
Category members GO Category GO:0003743 translation initiation factor activity Database 0.71
Category members GO Category GO:0043022 ribosome binding Database 0.33
Category members GO Category GO:0042256 mature ribosome assembly Database 0.3
Category members GO Category GO:0005882 intermediate filament Database 0


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