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Query: EEFSEC

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EEFSEC 0 -1.554 1.890 -1.240 -1.222 0.489 0.126

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EEFSEC Ubiquitylation K38 -0.599 -0.349 _ALSTTASTAAFDK(gl)QPQSR_

Background Information for EEFSEC:


Pubmed-EEFSEC »
Uniprot-EEFSEC »
Biogrid-EEFSEC »
ProteomicsDB-EEFSEC »

Tumorportal-EEFSEC »
COSMIC-EEFSEC »
GenomeRNAi-EEFSEC »
Genecards-EEFSEC


Protein-protein Interactions for EEFSEC
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GSPT1;GSPT2 Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait PARD6B Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SOX17 Cat. description Hein, Mann, Cell 2015


Protein Domains in EEFSEC
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members EF_GTP-bd_dom IPR000795 1.57
Category members Transl_B-barrel IPR009000 0.24
Category members CobW/HypB/UreG_dom IPR003495 0.04
Category members Transl_elong_EFTu/EF1A_2 IPR004161 0
Category members Transl_elong_EF1A/Init_IF2_C IPR009001 0


Protein complexes (CORUM database) featuring EEFSEC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EEFSEC
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0030529 ribonucleoprotein complex Database 8.45
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0006184 GTP catabolic process Database 0.29
Category members GO Category GO:0005525 GTP binding Database 0.16
Category members GO Category GO:0003924 GTPase activity Database 0.16
Category members GO Category GO:0003746 translation elongation factor activity Database 0.08
Category members GO Category GO:0001514 selenocysteine incorporation Database 0.05
Category members GO Category GO:0035368 selenocysteine insertion sequence binding Database 0.04
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0043021 ribonucleoprotein complex binding Database 0


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