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Query: EEF1G

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EEF1G 2 6.603 -1.850 3.470
EEF1G 2 6.603 -1.850 3.470 0.073 0.779 0.176 0.443 0.225

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
EEF1G Ubiquitylation K344 1.618 _STFVLDEFK(gl)R_
EEF1G Ubiquitylation K262 0.320 1.041 _LCEK(gl)MAQFDAKK_
EEF1G Ubiquitylation K67 0.885 _AFK(gl)ALIAAQYSGAQVR_
EEF1G Ubiquitylation K277 -0.220 0.774 _FAETQPK(gl)KDTPR_
EEF1G Ubiquitylation K258 0.599 0.634 _AVLGEVK(gl)LCEK_
EEF1G Ubiquitylation K270 -0.557 0.096 _K(gl)FAETQPK_
EEF1G Ubiquitylation K327 -0.410 -0.020 _AK(gl)DPFAHLPK_
EEF1G Ubiquitylation K484 -0.237 _AFNQGK(gl)IFK_
EEF1G Ubiquitylation K487 -0.407 _AFNQGKIFK(gl)_

Background Information for EEF1G:





Protein-protein Interactions for EEF1G

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CHMP4B Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1A1;EEF1A1P5 Cat. description Hein, Mann, Cell 2015
Category members IP bait ERBB2 Cat. description Hein, Mann, Cell 2015
Category members IP bait EXOSC9 Cat. description Hein, Mann, Cell 2015
Category members IP bait KIF20B Cat. description Hein, Mann, Cell 2015
Category members IP bait KTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MTA2 Cat. description Hein, Mann, Cell 2015
Category members IP bait PKN2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SLC33A1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SPIRE2 Cat. description Hein, Mann, Cell 2015
Category members IP bait EEF1G Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EEF1G

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glutathione-S-Trfase_C-like IPR010987 0.23
Category members Thioredoxin-like_fold IPR012336 0.16
Category members Glutathione_S-Trfase_N IPR004045 0
Category members GST_C IPR004046 0


Protein complexes (CORUM database) featuring EEF1G

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 1335 SNW1 complex Database 3.59


Categories featuring EEF1G

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Pathway Pathway_456 REACTOME_TRANSLATION 0 INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0006412 translation Database INF
Category members GO Category GO:0006414 translational elongation Database INF
Category members GO Category GO:0010467 gene expression Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005853 eukaryotic translation elongation factor 1 complex Database 0.6
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0003746 translation elongation factor activity Database 0.08
Category members GO Category GO:0009615 response to virus Database 0


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