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Query: EARS2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
EARS2 0 -1.510 -0.906 0.314 -1.304 -0.291 0.677

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence

Background Information for EARS2:


Pubmed-EARS2 »
Uniprot-EARS2 »
Biogrid-EARS2 »
ProteomicsDB-EARS2 »

Tumorportal-EARS2 »
COSMIC-EARS2 »
GenomeRNAi-EARS2 »
Genecards-EARS2


Protein-protein Interactions for EARS2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BSG Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MAS1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in EARS2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Glu/Gln-tRNA-synth IPR000924 0.09
Category members Glu/Gln-tRNA-synth_Ib_cat-dom IPR020058 0.09


Protein complexes (CORUM database) featuring EARS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring EARS2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0010467 gene expression Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0000166 nucleotide binding Database 5.91
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members Pathway Pathway_202 REACTOME_TRNA_AMINOACYLATION 0 1.34
Category members GO Category GO:0006418 tRNA aminoacylation for protein translation Database 0.91
Category members Pathway Pathway_409 KEGG_AMINOACYL_TRNA_BIOSYNTHESIS 0 0.82
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds Database 0.42
Category members Pathway Pathway_81 KEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM 0 0.01
Category members Pathway Pathway_203 REACTOME_MITOCHONDRIAL_TRNA_AMINOACYLATION 0 0
Category members GO Category GO:0000049 tRNA binding Database 0
Category members GO Category GO:0004818 glutamate-tRNA ligase activity Database 0
Category members GO Category GO:0006424 glutamyl-tRNA aminoacylation Database 0
Category members GO Category GO:0043039 tRNA aminoacylation Database 0


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