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Query: DYRK1B

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DYRK1B 0 1.800 0.340 -0.930

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DYRK1B Phosphorylation Y321 0.876 0.924 _IYQY(ph)IQSR_

Background Information for DYRK1B:


Pubmed-DYRK1B »
Uniprot-DYRK1B »
Biogrid-DYRK1B »
ProteomicsDB-DYRK1B »

Tumorportal-DYRK1B »
COSMIC-DYRK1B »
GenomeRNAi-DYRK1B »
Genecards-DYRK1B


Protein-protein Interactions for DYRK1B
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait C10orf71 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C19orf21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DCAF7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM117B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM53C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LZTS2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DYRK1B
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Kinase-like_dom IPR011009 0.03
Category members Prot_kinase_dom IPR000719 0
Category members Ser-Thr/Tyr_kinase_cat_dom IPR001245 0
Category members Ser/Thr_dual-sp_kinase IPR002290 0
Category members Tyr_kinase_cat_dom IPR020635 0


Protein complexes (CORUM database) featuring DYRK1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DYRK1B
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0003713 transcription coactivator activity Database 3.68
Category members GO Category GO:0004674 protein serine/threonine kinase activity Database 0.66
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0045893 positive regulation of transcription, DNA-dependent Database 0.28
Category members GO Category GO:0004672 protein kinase activity Database 0.19
Category members GO Category GO:0007520 myoblast fusion Database 0.11
Category members GO Category GO:0006468 protein phosphorylation Database 0.04
Category members GO Category GO:0004713 protein tyrosine kinase activity Database 0.01
Category members Pathway Pathway_1154 BIOCARTA_SHH_PATHWAY 0 0
Category members GO Category GO:0004712 protein serine/threonine/tyrosine kinase activity Database 0
Category members GO Category GO:0016772 transferase activity, transferring phosphorus-containing groups Database 0


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