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Query: DYNC1LI2

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DYNC1LI2 0 1.489 -0.700 1.220

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DYNC1LI2 Phosphorylation S446 -0.866 0.239 _KTGSPGS(ph)PGAGGVQSTAK_
DYNC1LI2 Phosphorylation S194 0.030 0.201 _DFQDYMEPEEGCQGS(ph)PQRR_
DYNC1LI2 Phosphorylation S205 -0.078 _GPLTSGS(ph)DEENVALPLGDNVLTHNLGIPVLVVCTK_

Background Information for DYNC1LI2:


Pubmed-DYNC1LI2 »
Uniprot-DYNC1LI2 »
Biogrid-DYNC1LI2 »
ProteomicsDB-DYNC1LI2 »

Tumorportal-DYNC1LI2 »
COSMIC-DYNC1LI2 »
GenomeRNAi-DYNC1LI2 »
Genecards-DYNC1LI2


Protein-protein Interactions for DYNC1LI2
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNC1H1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNC1LI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLRB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAFAH1B1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C2CD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DYNC1I1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DYNC1I2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCBP4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DYNC1LI2
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Dynein_light_int_chain IPR022780 0.07


Protein complexes (CORUM database) featuring DYNC1LI2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DYNC1LI2
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members Pathway Pathway_621 REACTOME_ADAPTIVE_IMMUNE_SYSTEM 0 4.72
Category members Pathway Pathway_458 REACTOME_IMMUNE_SYSTEM 0 3
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members GO Category GO:0005813 centrosome Database 0.75
Category members Pathway Pathway_1265 REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION 0 0.6
Category members GO Category GO:0000226 microtubule cytoskeleton organization Database 0.5
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members GO Category GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II Database 0.13
Category members Pathway Pathway_266 KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION 0 0
Category members GO Category GO:0005868 cytoplasmic dynein complex Database 0
Category members GO Category GO:0006810 transport Database 0
Category members GO Category GO:0051642 centrosome localization Database 0


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