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Query: DYNC1LI1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DYNC1LI1 0 0.033 -1.030 0.970 0.718 1.054 -0.006

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DYNC1LI1 Phosphorylation S222 0.358 _NTASQEDKDDS(ph)VVLPLGADTLTHNLGIPVLVVCTK_
DYNC1LI1 Phosphorylation S207 -0.595 -0.347 _DFQEYVEPGEDFPAS(ph)PQRR_
DYNC1LI1 Phosphorylation S414 0.215 -0.371 _SVS(ph)SNVASVSPIPAGSK_
DYNC1LI1 Phosphorylation S421 -1.661 -0.915 _SVSSNVASVS(ph)PIPAGSK_
DYNC1LI1 Phosphorylation S516 -0.208 -1.103 _KPVTVS(ph)PTTPTS(ph)PTEGEAS_
DYNC1LI1 Phosphorylation T515 -1.148 _KPVTVS(ph)PTTPT(ph)SPTEGEAS_
DYNC1LI1 Phosphorylation T518 -0.377 -1.333 _KPVTVSPTTPTSPT(ph)EGEAS_
DYNC1LI1 Ubiquitylation K385 -1.844 -1.432 _LQSLLAK(gl)QPPTAAGRPVDASPR_
DYNC1LI1 Phosphorylation S510 -1.903 -1.992 _KPVTVS(ph)PTTPTS(ph)PTEGEAS_
DYNC1LI1 Phosphorylation S412 -0.055 _S(ph)VSSNVASVSPIPAGSK_

Background Information for DYNC1LI1:


Pubmed-DYNC1LI1 »
Uniprot-DYNC1LI1 »
Biogrid-DYNC1LI1 »
ProteomicsDB-DYNC1LI1 »

Tumorportal-DYNC1LI1 »
COSMIC-DYNC1LI1 »
GenomeRNAi-DYNC1LI1 »
Genecards-DYNC1LI1


Protein-protein Interactions for DYNC1LI1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CENPE Cat. description Hein, Mann, Cell 2015
Category members IP bait DCTN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNC1H1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNC1LI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLL1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DYNLRB1 Cat. description Hein, Mann, Cell 2015
Category members IP bait PAFAH1B1 Cat. description Hein, Mann, Cell 2015
Category members IP bait C2CD2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DYNC1I1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TRPT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DYNC1LI1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Dynein_light_int_chain IPR022780 0.07


Protein complexes (CORUM database) featuring DYNC1LI1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DYNC1LI1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0019048 modulation by virus of host morphology or physiology Database 7.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0000776 kinetochore Database 2.24
Category members GO Category GO:0007067 mitosis Database 2.23
Category members GO Category GO:0005874 microtubule Database 1.21
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0007018 microtubule-based movement Database 0.75
Category members GO Category GO:0005813 centrosome Database 0.75
Category members GO Category GO:0003777 microtubule motor activity Database 0.49
Category members GO Category GO:0000922 spindle pole Database 0.35
Category members GO Category GO:0000777 condensed chromosome kinetochore Database 0.32
Category members Pathway Pathway_266 KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION 0 0
Category members GO Category GO:0005868 cytoplasmic dynein complex Database 0
Category members GO Category GO:0006810 transport Database 0


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