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bioLOGIC Data

Query: DPYSL5

RNAi screen result	RNAPII IP (PI)	CSB IP	CSB IP (PI)	Chrom.	Chrom. (PI)	Phosphorylation	Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:
Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen

Gene name	Point score	Z-score sums	RNAi high	RNAi low	RNAPII-IP (PI)	CSB-IP	CSB-IP (PI)	Chrom.	Chrom. (PI)
DPYSL5	0	0.000	0.790	-0.740	-0.911

PTM Sites:
Back to Protein Results | Red/green: hit at lower/upper end of the respective screen

Gene name	PTM type	PTM site	UV	UV (PI)	Sequence

Background Information for DPYSL5:

Pubmed-DPYSL5 »

Uniprot-DPYSL5 »

Biogrid-DPYSL5 »

ProteomicsDB-DPYSL5 »

Tumorportal-DPYSL5 »

COSMIC-DPYSL5 »

GenomeRNAi-DPYSL5 »

Genecards-DPYSL5

Protein-protein Interactions for DPYSL5

Show screen data for	Category Name and Description	Link to cat description	Data Source
Category members	IP bait C14orf104	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait DGUOK	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait DPYS	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait DPYSL5	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait FAM19A3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait HAX1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait KLHDC3	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait LGALS7	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait NUFIP1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait SHMT1	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015
Category members	IP bait TGIF2LY	Cat. description	BioPlex, Huttlin, Gygi, Cell 2015

Protein Domains in DPYSL5

	Domain name	Domain Description	TC-NER relevance -log10(p-value)
Category members	Hydantoinase/dihydroPyrase	IPR011778	0.23
Category members	Amidohydro_1	IPR006680	0
Category members	Metal-dep_hydrolase_composite	IPR011059	0

Protein complexes (CORUM database) featuring DPYSL5

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)

Categories featuring DPYSL5

	Category Type	Category ID	Category Name	Data Source	TC-NER relevance -log10(p-value)
Category members	GO Category	GO:0005515	protein binding	Database	INF
Category members	GO Category	GO:0005829	cytosol	Database	INF
Category members	GO Category	GO:0005737	cytoplasm	Database	12.81
Category members	DDR Literature	pubmedid:19647519	Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation		3.6
Category members	GO Category	GO:0043234	protein complex	Database	2.73
Category members	Pathway	Pathway_673	REACTOME_AXON_GUIDANCE	0	1.06
Category members	Pathway	Pathway_674	REACTOME_SEMAPHORIN_INTERACTIONS	0	0.96
Category members	Pathway	Pathway_42	REACTOME_DEVELOPMENTAL_BIOLOGY	0	0.32
Category members	GO Category	GO:0030425	dendrite	Database	0.26
Category members	GO Category	GO:0016787	hydrolase activity	Database	0.22
Category members	GO Category	GO:0006208	pyrimidine nucleobase catabolic process	Database	0.22
Category members	Pathway	Pathway_1282	REACTOME_CRMPS_IN_SEMA3A_SIGNALING	0	0.17
Category members	GO Category	GO:0007411	axon guidance	Database	0.13
Category members	GO Category	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	Database	0.04
Category members	Pathway	Pathway_1034	KEGG_AXON_GUIDANCE	0	0.04
Category members	GO Category	GO:0007165	signal transduction	Database	0
Category members	GO Category	GO:0007399	nervous system development	Database	0
Category members	GO Category	GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	Database	0
Category members	GO Category	GO:0030182	neuron differentiation	Database	0
Category members	GO Category	GO:0043025	neuronal cell body	Database	0