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Query: DPM1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DPM1 0 2.234 0.070 -0.350 -0.276 0.551 0.359

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DPM1 Phosphorylation S3 -0.133 1.347 _(ac)AS(ph)LEVSRS(ph)PR_
DPM1 Phosphorylation S7 0.079 0.135 _(ac)ASLEVS(ph)RSPRR_
DPM1 Phosphorylation S9 0.253 0.027 _(ac)AS(ph)LEVSRS(ph)PR_

Background Information for DPM1:


Pubmed-DPM1 »
Uniprot-DPM1 »
Biogrid-DPM1 »
ProteomicsDB-DPM1 »

Tumorportal-DPM1 »
COSMIC-DPM1 »
GenomeRNAi-DPM1 »
Genecards-DPM1


Protein-protein Interactions for DPM1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait AZI1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CCT4 Cat. description Hein, Mann, Cell 2015
Category members IP bait ELMSAN1 Cat. description Hein, Mann, Cell 2015
Category members IP bait M6PR Cat. description Hein, Mann, Cell 2015
Category members IP bait TUBG1 Cat. description Hein, Mann, Cell 2015
Category members IP bait UBR5 Cat. description Hein, Mann, Cell 2015


Protein Domains in DPM1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Nucleotide-diphossugar_trans IPR029044 0.21
Category members Glyco_trans_2-like IPR001173 0.17


Protein complexes (CORUM database) featuring DPM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 5244 Dolichol-phosphate mannose (DPM) synthase Database 0


Categories featuring DPM1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members Pathway Pathway_11 REACTOME_METABOLISM_OF_PROTEINS 0 12.01
Category members GO Category GO:0044267 cellular protein metabolic process Database 10.42
Category members GO Category GO:0005789 endoplasmic reticulum membrane Database 1.57
Category members GO Category GO:0005783 endoplasmic reticulum Database 0.62
Category members GO Category GO:0016020 membrane Database 0.52
Category members GO Category GO:0043231 intracellular membrane-bounded organelle Database 0.43
Category members GO Category GO:0006488 dolichol-linked oligosaccharide biosynthetic process Database 0.28
Category members GO Category GO:0016757 transferase activity, transferring glycosyl groups Database 0.19
Category members Pathway Pathway_93 REACTOME_BIOSYNTHESIS_OF_THE_N_GLYCAN_PRECURSOR_DOLICHOL_LIPID_LINKED_OLIGOSACCHARIDE_LLO_AND_TRANSFER_TO_A_NASCENT_PROTEIN 0 0.18
Category members GO Category GO:0006501 C-terminal protein lipidation Database 0.1
Category members GO Category GO:0005537 mannose binding Database 0.07
Category members Pathway Pathway_461 REACTOME_POST_TRANSLATIONAL_MODIFICATION_SYNTHESIS_OF_GPI_ANCHORED_PROTEINS 0 0.04
Category members Pathway Pathway_109 KEGG_N_GLYCAN_BIOSYNTHESIS 0 0.04
Category members Pathway Pathway_92 REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS 0 0
Category members Pathway Pathway_94 REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION 0 0
Category members Pathway Pathway_95 REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION 0 0
Category members Disease phenotype Congenital_Disorders_of_Glycosylation Congenital Disorders of Glycosylation Database 0
Category members GO Category GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity Database 0
Category members GO Category GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity Database 0
Category members GO Category GO:0006506 GPI anchor biosynthetic process Database 0
Category members GO Category GO:0018279 protein N-linked glycosylation via asparagine Database 0
Category members GO Category GO:0019348 dolichol metabolic process Database 0
Category members GO Category GO:0019673 GDP-mannose metabolic process Database 0
Category members GO Category GO:0033185 dolichol-phosphate-mannose synthase complex Database 0
Category members GO Category GO:0035268 protein mannosylation Database 0
Category members GO Category GO:0035269 protein O-linked mannosylation Database 0
Category members GO Category GO:0043687 post-translational protein modification Database 0


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