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Query: DOCK5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DOCK5 0 0.783 0.550 -0.090

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DOCK5 Phosphorylation S1834 0.783 _NS(ph)TELAPPLPVR_

Background Information for DOCK5:


Pubmed-DOCK5 »
Uniprot-DOCK5 »
Biogrid-DOCK5 »
ProteomicsDB-DOCK5 »

Tumorportal-DOCK5 »
COSMIC-DOCK5 »
GenomeRNAi-DOCK5 »
Genecards-DOCK5


Protein-protein Interactions for DOCK5
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDC37 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDCA5 Cat. description Hein, Mann, Cell 2015
Category members IP bait CRKL Cat. description Hein, Mann, Cell 2015
Category members IP bait LGALS3BP Cat. description Hein, Mann, Cell 2015
Category members IP bait ROCK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SMEK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DOCK5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELMO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELMO3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DOCK5
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members ARM-type_fold IPR016024 9.26
Category members SH3_2 IPR011511 0.08
Category members SH3_domain IPR001452 0
Category members DOCK_C IPR010703 0


Protein complexes (CORUM database) featuring DOCK5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DOCK5
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005488 binding Database 9.32
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0


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