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Query: DOCK4

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DOCK4 0 1.172 -0.420 0.110

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DOCK4 Phosphorylation S1853 0.304 _HTTSVS(ph)PSPAGR_
DOCK4 Phosphorylation S1665 -0.102 _NSAPASVS(ph)PDGTR_
DOCK4 Phosphorylation T1669 0.625 _NSAPASVS(ph)PDGTR_
DOCK4 Phosphorylation S1745 -0.498 _AS(ph)PLLSDK_
DOCK4 Phosphorylation T1850 0.758 _HTT(ph)SVSPSPAGR_

Background Information for DOCK4:


Pubmed-DOCK4 »
Uniprot-DOCK4 »
Biogrid-DOCK4 »
ProteomicsDB-DOCK4 »

Tumorportal-DOCK4 »
COSMIC-DOCK4 »
GenomeRNAi-DOCK4 »
Genecards-DOCK4


Protein-protein Interactions for DOCK4
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARRB1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELMO1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ELMO3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ERMAP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GRB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait STAT1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait VSIG8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DOCK4
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members Rho_GTPase_activation_prot IPR008936 0.53
Category members SH3_2 IPR011511 0.08
Category members C2_dom IPR000008 0
Category members SH3_domain IPR001452 0
Category members DOCK_C IPR010703 0


Protein complexes (CORUM database) featuring DOCK4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DOCK4
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members Pathway Pathway_561 PID_PDGFRB_PATHWAY 0 1.18
Category members GO Category GO:0016020 membrane Database 0.52
Category members Pathway Pathway_53 REACTOME_HEMOSTASIS 0 0.4
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0030165 PDZ domain binding Database 0.29
Category members GO Category GO:0048365 Rac GTPase binding Database 0.1
Category members Pathway Pathway_385 REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION 0 0.07
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0012505 endomembrane system Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0030675 Rac GTPase activator activity Database 0
Category members GO Category GO:0030971 receptor tyrosine kinase binding Database 0
Category members GO Category GO:0032420 stereocilium Database 0
Category members GO Category GO:0032421 stereocilium bundle Database 0
Category members GO Category GO:0032855 positive regulation of Rac GTPase activity Database 0
Category members GO Category GO:0060326 cell chemotaxis Database 0


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