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Query: DOCK11

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DOCK11 0 3.320 -0.840 1.200 0.433 0.251 0.311

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DOCK11 Phosphorylation S437 0.259 _EMLWGSSTQLAS(ph)DGSPK_
DOCK11 Phosphorylation S12 0.246 _RLS(ph)KPGTAAELR_
DOCK11 Phosphorylation S1240 0.135 _EDSRGS(ph)LIPEGATGFPDQGNTGENTR_
DOCK11 Phosphorylation S1237 0.049 0.017 _EDS(ph)RGSLIPEGATGFPDQGNTGENTR_
DOCK11 Ubiquitylation K498 0.817 _VLQGNITHCAEPYIK(gl)NSDPVK_

Background Information for DOCK11:


Pubmed-DOCK11 »
Uniprot-DOCK11 »
Biogrid-DOCK11 »
ProteomicsDB-DOCK11 »

Tumorportal-DOCK11 »
COSMIC-DOCK11 »
GenomeRNAi-DOCK11 »
Genecards-DOCK11


Protein-protein Interactions for DOCK11
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ARHGAP22 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait C10orf88 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait DENR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GCHFR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GORASP1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait UQCRH Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DOCK11
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members PH_domain IPR001849 0.14
Category members DOCK_C IPR010703 0
Category members DOCK_C/D_N IPR021816 0


Protein complexes (CORUM database) featuring DOCK11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DOCK11
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005829 cytosol Database INF
Category members DDR Literature pubmedid:19647519 Paulsen et al., 2009 siRNA screen for g-H2A.x phosphorylation 3.6
Category members GO Category GO:0017048 Rho GTPase binding Database 0.69
Category members GO Category GO:0007596 blood coagulation Database 0.4
Category members GO Category GO:0007264 small GTPase mediated signal transduction Database 0.37
Category members GO Category GO:0005089 Rho guanyl-nucleotide exchange factor activity Database 0.08
Category members Pathway Pathway_293 PID_CDC42_REG_PATHWAY 0 0.05
Category members GO Category GO:0005085 guanyl-nucleotide exchange factor activity Database 0


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