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Query: DLG5

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DLG5 0 -1.275 -0.250 0.030

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DLG5 Phosphorylation S1254 0.219 _ATHGSNS(ph)LPSSAR_
DLG5 Phosphorylation S132 -1.278 -1.199 _APS(ph)PPPLLTDQQVNEK_
DLG5 Ubiquitylation K63 -0.246 _LLLAK(gl)ER_

Background Information for DLG5:





Protein-protein Interactions for DLG5

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CDK1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP135 Cat. description Hein, Mann, Cell 2015
Category members IP bait DLG5 Cat. description Hein, Mann, Cell 2015
Category members IP bait FGFR1OP Cat. description Hein, Mann, Cell 2015
Category members IP bait MARK2 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYH9 Cat. description Hein, Mann, Cell 2015
Category members IP bait NAA11 Cat. description Hein, Mann, Cell 2015
Category members IP bait TPM1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DLG5

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members GK/Ca_channel_bsu IPR008145 1.36
Category members Guanylate_kin-like IPR008144 1.32
Category members DEATH-like_dom IPR011029 1.15
Category members CARD IPR001315 0.55
Category members PDZ IPR001478 0.15
Category members SH3_domain IPR001452 0


Protein complexes (CORUM database) featuring DLG5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DLG5

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005886 plasma membrane Database 1.21
Category members GO Category GO:0005913 cell-cell adherens junction Database 1.05
Category members GO Category GO:0042981 regulation of apoptotic process Database 0.79
Category members GO Category GO:0008092 cytoskeletal protein binding Database 0.5
Category members GO Category GO:0008013 beta-catenin binding Database 0.35
Category members GO Category GO:0005622 intracellular Database 0.32
Category members GO Category GO:0008285 negative regulation of cell proliferation Database 0.28
Category members GO Category GO:0007165 signal transduction Database 0
Category members GO Category GO:0016337 cell-cell adhesion Database 0
Category members GO Category GO:0030159 receptor signaling complex scaffold activity Database 0
Category members GO Category GO:0035556 intracellular signal transduction Database 0


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