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Query: DHX36

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHX36 2 2.768 -2.190 4.200 -0.545 -0.667 -0.353 -1.117 -0.161

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DHX36 Phosphorylation S2 0.179 1.998 _(ac)S(ph)YDYHQNWGR_
DHX36 Ubiquitylation K862 -1.119 _VYTK(gl)TDGLVAVHPK_

Background Information for DHX36:


Pubmed-DHX36 »
Uniprot-DHX36 »
Biogrid-DHX36 »
ProteomicsDB-DHX36 »

Tumorportal-DHX36 »
COSMIC-DHX36 »
GenomeRNAi-DHX36 »
Genecards-DHX36


Protein-protein Interactions for DHX36
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait CCDC93 Cat. description Hein, Mann, Cell 2015
Category members IP bait CEP85L Cat. description Hein, Mann, Cell 2015
Category members IP bait MAX Cat. description Hein, Mann, Cell 2015
Category members IP bait MBD2 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL35 Cat. description Hein, Mann, Cell 2015
Category members IP bait VPS28 Cat. description Hein, Mann, Cell 2015
Category members IP bait BYSL Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB38 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DHX36
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members DUF1605 IPR011709 0.02
Category members Helicase-assoc_dom IPR007502 0


Protein complexes (CORUM database) featuring DHX36
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DHX36
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members DDR Literature pubmedid:24332808 Marechal et al., 2014 RPA-mediated recruitment INF
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0005829 cytosol Database INF
Category members GO Category GO:0005737 cytoplasm Database 12.81
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0032481 positive regulation of type I interferon production Database 0.54
Category members GO Category GO:0003725 double-stranded RNA binding Database 0.1
Category members GO Category GO:0045087 innate immune response Database 0.05
Category members GO Category GO:0009615 response to virus Database 0
Category members GO Category GO:0043330 response to exogenous dsRNA Database 0


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