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Query: DHX16

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHX16 0 0.934 0.630 -1.000 -0.397 -0.261 -0.209 -0.496 -0.108

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DHX16 Phosphorylation S103 0.525 1.462 _LLEDS(ph)EESSEETVSR_
DHX16 Phosphorylation S106 0.698 0.697 _LLEDS(ph)EES(ph)SEETVSR_
DHX16 Phosphorylation S160 0.943 0.503 _QQTEKPES(ph)EDEWER_
DHX16 Phosphorylation T155 0.840 0.314 _QQT(ph)EKPESEDEWER_
DHX16 Phosphorylation S107 0.644 _LLEDS(ph)EESS(ph)EETVSR_

Background Information for DHX16:





Protein-protein Interactions for DHX16

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait GPKOW Cat. description Hein, Mann, Cell 2015
Category members IP bait JAK3 Cat. description Hein, Mann, Cell 2015
Category members IP bait POLH Cat. description Hein, Mann, Cell 2015
Category members IP bait PRKCD Cat. description Hein, Mann, Cell 2015
Category members IP bait SMAD3 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRSF1 Cat. description Hein, Mann, Cell 2015
Category members IP bait CDKL5 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FADS3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GPKOW Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SETDB2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TTC29 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DHX16

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members DUF1605 IPR011709 0.02
Category members Helicase-assoc_dom IPR007502 0


Protein complexes (CORUM database) featuring DHX16

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members Corum 351 Spliceosome Database 9.3
Category members Corum 1141 CF IIAm complex (Cleavage factor IIAm complex) Database 2.57


Categories featuring DHX16

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0008380 RNA splicing Database 10.77
Category members Pathway Pathway_851 KEGG_SPLICEOSOME 0 7.94
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0006397 mRNA processing Database 3.76
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0003724 RNA helicase activity Database 0.07


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