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Query: DHFRL1

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DHFRL1 0 -0.149 0.230 -0.640 -0.938 -0.400

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DHFRL1 Ubiquitylation K56 -0.219 _QNLVIMGK(gl)K_
DHFRL1 Ubiquitylation K55 -0.547 _QNLVIMGK(gl)K_
DHFRL1 Ubiquitylation K158 -1.504 _YK(gl)LLPEYPGVLSDVQEEK_
DHFRL1 Ubiquitylation K81 -1.954 _ELK(gl)EPPQGAHFLSR_
DHFRL1 Ubiquitylation K99 -2.021 _SLDDALK(gl)LTEQPELANK_
DHFRL1 Ubiquitylation K174 -2.693 _LLPEYPGVLSDVQEEK(gl)GIK_
DHFRL1 Ubiquitylation K133 1.408 _EAM(ox)NHPGHLK(gl)LFVTR_

Background Information for DHFRL1:


Pubmed-DHFRL1 »
Uniprot-DHFRL1 »
Biogrid-DHFRL1 »
ProteomicsDB-DHFRL1 »

Tumorportal-DHFRL1 »
COSMIC-DHFRL1 »
GenomeRNAi-DHFRL1 »
Genecards-DHFRL1


Protein-protein Interactions for DHFRL1
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ADAM21 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ADAM33 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CBLN4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait CD1B Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FAM5C Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GAA Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GML Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HTR3A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait IDS Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait LIPH Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MPPE1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait OLFM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDH20 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PCDHA12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLAUR Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PLTP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PTCH1 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINA6 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SERPINA7 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ST3GAL4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TCTN2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMEM25 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait TMPRSS11B Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DHFRL1
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DHFR_dom IPR001796 0
Category members DHFR IPR012259 0
Category members DHFR-like_dom IPR024072 0


Protein complexes (CORUM database) featuring DHFRL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DHFRL1
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005739 mitochondrion Database 1.67
Category members GO Category GO:0003729 mRNA binding Database 1.38
Category members GO Category GO:0046653 tetrahydrofolate metabolic process Database 0.91
Category members GO Category GO:0005759 mitochondrial matrix Database 0.59
Category members GO Category GO:0009165 nucleotide biosynthetic process Database 0.17
Category members GO Category GO:0005743 mitochondrial inner membrane Database 0.15
Category members GO Category GO:0004146 dihydrofolate reductase activity Database 0
Category members GO Category GO:0006545 glycine biosynthetic process Database 0
Category members GO Category GO:0006730 one-carbon metabolic process Database 0
Category members GO Category GO:0046654 tetrahydrofolate biosynthetic process Database 0
Category members GO Category GO:0050661 NADP binding Database 0
Category members GO Category GO:0055114 oxidation-reduction process Database 0


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