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Query: DENND1A

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DENND1A 0 0.900 -0.530 0.180

PTM Sites:

Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DENND1A Phosphorylation S455 -0.067 0.594 _S(ph)LEDLRAPK_
DENND1A Phosphorylation S409 0.126 0.405 _ESDSAEGDEAES(ph)PEQQVR_
DENND1A Phosphorylation S519 -0.933 _LWSLGQDDMAIPSKPPAAS(ph)PEKPSALLGNSLALPR_
DENND1A Phosphorylation T570 -1.565 -1.192 _KT(ph)PELGIVPPPPIPR_
DENND1A Phosphorylation S399 -0.061 _ES(ph)DSAEGDEAESPEQQVR_

Background Information for DENND1A:





Protein-protein Interactions for DENND1A

Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait ANAPC15 Cat. description Hein, Mann, Cell 2015
Category members IP bait ATL2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTB Cat. description Hein, Mann, Cell 2015
Category members IP bait CLTC Cat. description Hein, Mann, Cell 2015
Category members IP bait GAK Cat. description Hein, Mann, Cell 2015
Category members IP bait GTSE1 Cat. description Hein, Mann, Cell 2015
Category members IP bait LIMA1 Cat. description Hein, Mann, Cell 2015
Category members IP bait MYO1C Cat. description Hein, Mann, Cell 2015
Category members IP bait PICALM Cat. description Hein, Mann, Cell 2015
Category members IP bait SEC24C Cat. description Hein, Mann, Cell 2015
Category members IP bait TMOD3 Cat. description Hein, Mann, Cell 2015


Protein Domains in DENND1A

Domain name Domain Description TC-NER relevance -log10(p-value)
Category members DENN_dom IPR001194 0
Category members dDENN_dom IPR005112 0
Category members uDENN_dom IPR005113 0


Protein complexes (CORUM database) featuring DENND1A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DENND1A

Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0005515 protein binding Database INF
Category members GO Category GO:0015031 protein transport Database 3.48
Category members GO Category GO:0006897 endocytosis Database 0.31
Category members GO Category GO:0030425 dendrite Database 0.26
Category members GO Category GO:0030665 clathrin-coated vesicle membrane Database 0.24
Category members GO Category GO:0030136 clathrin-coated vesicle Database 0.06
Category members GO Category GO:0045202 synapse Database 0.06
Category members GO Category GO:0048488 synaptic vesicle endocytosis Database 0.05
Category members GO Category GO:0017112 Rab guanyl-nucleotide exchange factor activity Database 0
Category members GO Category GO:0017124 SH3 domain binding Database 0
Category members GO Category GO:0030054 cell junction Database 0
Category members GO Category GO:0032483 regulation of Rab protein signal transduction Database 0
Category members GO Category GO:0042734 presynaptic membrane Database 0
Category members GO Category GO:0043025 neuronal cell body Database 0


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