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Query: DDX54

RNAi screen result RNAPII IP (PI) CSB IP CSB IP (PI) Chrom. Chrom. (PI) Phosphorylation Ubiquitylation
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[Click on the plots to view the data selection in the respective scatterplot]

Protein Results:

 Results for post-translational modifications: see below | Red/green: hit at lower/upper end of the respective screen
Gene name Point score Z-score sums RNAi high RNAi low RNAPII-IP (PI) CSB-IP CSB-IP (PI) Chrom. Chrom. (PI)
DDX54 1 4.324 -0.350 -0.090 -0.557 -0.158

PTM Sites:

 Back to Protein Results | Red/green: hit at lower/upper end of the respective screen
Gene name PTM type PTM site UV UV (PI) Sequence
DDX54 Ubiquitylation K764 1.075 2.500 _YISSSYK(gl)R_
DDX54 Phosphorylation S782 0.699 0.855 _IDDRDS(ph)DEEGASDR_
DDX54 Phosphorylation S75 -0.422 -0.543 _LGPGRPLPTFPTSECTS(ph)DVEPDTR_
DDX54 Phosphorylation T74 -0.548 _LGPGRPLPTFPTSECT(ph)SDVEPDTR_

Background Information for DDX54:


Pubmed-DDX54 »
Uniprot-DDX54 »
Biogrid-DDX54 »
ProteomicsDB-DDX54 »

Tumorportal-DDX54 »
COSMIC-DDX54 »
GenomeRNAi-DDX54 »
Genecards-DDX54


Protein-protein Interactions for DDX54
Show screen data for Category Name and Description Link to cat description Data Source
Category members IP bait BAG2 Cat. description Hein, Mann, Cell 2015
Category members IP bait CBX8 Cat. description Hein, Mann, Cell 2015
Category members IP bait FAM83H Cat. description Hein, Mann, Cell 2015
Category members IP bait HNRNPU Cat. description Hein, Mann, Cell 2015
Category members IP bait NOP56 Cat. description Hein, Mann, Cell 2015
Category members IP bait RPL10 Cat. description Hein, Mann, Cell 2015
Category members IP bait RRBP1 Cat. description Hein, Mann, Cell 2015
Category members IP bait SRP72 Cat. description Hein, Mann, Cell 2015
Category members IP bait TNPO1 Cat. description Hein, Mann, Cell 2015
Category members IP bait DGCR8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF3 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait FGF8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait GLTSCR2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait HIST1H1T Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MECP2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait MKI67IP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait NOL12 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PDGFB Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait PPAN Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM34 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RBM4 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPL18A Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RPS14 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait RRP8 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait SYNCRIP Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZBTB48 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF2 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF512 Cat. description BioPlex, Huttlin, Gygi, Cell 2015
Category members IP bait ZNF692 Cat. description BioPlex, Huttlin, Gygi, Cell 2015


Protein Domains in DDX54
Domain name Domain Description TC-NER relevance -log10(p-value)
Category members P-loop_NTPase IPR027417 2.83
Category members Helicase_C IPR001650 2.48
Category members Helicase_ATP-bd IPR014001 2.48
Category members Helicase/UvrB_dom IPR006935 0.78
Category members DEAD/DEAH_box_helicase_dom IPR011545 0.35
Category members RNA_helicase_DEAD_Q_motif IPR014014 0.24


Protein complexes (CORUM database) featuring DDX54
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)


Categories featuring DDX54
Category Type Category ID Category Name Data Source TC-NER relevance -log10(p-value)
Category members GO Category GO:0003723 RNA binding Database INF
Category members GO Category GO:0005634 nucleus Database INF
Category members GO Category GO:0016070 RNA metabolic process Database INF
Category members GO Category GO:0005730 nucleolus Database 13.38
Category members GO Category GO:0005524 ATP binding Database 5.54
Category members GO Category GO:0004386 helicase activity Database 2.49
Category members GO Category GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides Database 1.64
Category members GO Category GO:0003677 DNA binding Database 1.53
Category members GO Category GO:0004004 ATP-dependent RNA helicase activity Database 1.43
Category members GO Category GO:0006351 transcription, DNA-templated Database 1.07
Category members Pathway Pathway_185 PID_ERA_GENOMIC_PATHWAY 0 1.05
Category members Pathway Pathway_1260 PID_ERB_GENOMIC_PATHWAY 0 1.04
Category members GO Category GO:0003676 nucleic acid binding Database 0.83
Category members GO Category GO:0008026 ATP-dependent helicase activity Database 0.79
Category members GO Category GO:0016787 hydrolase activity Database 0.22
Category members GO Category GO:0006396 RNA processing Database 0.17
Category members GO Category GO:0030520 intracellular estrogen receptor signaling pathway Database 0.06
Category members GO Category GO:0003714 transcription corepressor activity Database 0
Category members GO Category GO:0005102 receptor binding Database 0
Category members GO Category GO:0006355 regulation of transcription, DNA-dependent Database 0
Category members GO Category GO:0030331 estrogen receptor binding Database 0


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